In recent years, the integration of digital experimentation (DE) and design of experiments (DOE) services has revolutionized the design phase of the DBTL cycle, enhancing efficiency and accelerating innovation. CD Biosynsis is dedicated to providing professional digital experimentation and DOE services to help researchers around the world advance their cutting-edge research.
Digital experimentation involves the utilization of computational tools and simulations to model and forecast the dynamics of biological systems prior to their physically built and tested in the laboratory. This empowers researchers to probe into design possibilities, predict outcomes, and enhance designs before allocating resources to physical implementation. The prime benefits of digital experimentation encompass:
DOE denotes a methodical strategy for planning, conducting, and analyzing experiments with the objective of comprehending the impact of various factors (variables) on the performance of a system. Within the domain of synthetic biology, DOE aids researchers in optimizing the parameters of their biological systems to achieve intended results in a resource-efficient manner. Instead of modifying one variable sequentially, DOE involves changing multiple variables simultaneously under controlled conditions to reveal interactions and optimal settings. The pivotal advantages of DOE encompass:
Fig 1. Application of experimental design to solving water engineering problems. (Lee B C Y, et al., 2022)
During the design phase, researchers use digital experimentation tools to construct and simulate potential systems virtually. Concurrently, the principles of DOE facilitate the selection and manipulation of variables for optimal performance. This integrated methodology enables researchers to identify promising designs and parameter configurations prior to entering the physical Build and Test phases.
Creating accurate simulations of biological systems and corroborating their accuracy prior to the physical construction of a synthetic biology design enables an intuitive comprehension of the interplay between diverse components. This approach also predicts the behavior of the system under diverse conditions.
Explore a variety of design variants to support clients in swiftly iterating their designs. Clients can test different assumptions, adjust parameters, and evaluate the impact of alterations on system performance.
Enhance parameter configurations to optimize the performance of biological systems. Experiments are designed to methodically alter multiple variables, thereby determining the optimal combination of desirable outcomes.
Risk Mitigation and Cost Savings
Interactive Design Collaboration
CD Biosynsis provides our clients with a powerful approach to enhance the DBTL cycle by integrating digital experimentation and DOE into our synthetic biology platform.
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.