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Heme Protein Strain Engineering

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CD Biosynsis specializes in offering cutting-edge heme biosynthesis services. We leverage state-of-the-art techniques and expertise to enable the precise synthesis of heme, catering to a diverse range of research and industrial needs.

Background and Technical Advantages

Heme biosynthesis is a fundamental biological process responsible for the synthesis of heme, a crucial molecule that plays an indispensable role in various biological processes. Heme, often referred to as the "iron-porphyrin" complex, serves as the prosthetic group in hemoglobin, myoglobin, and a multitude of crucial enzymes.

New avenues of heme synthesis regulation. Fig 1. New avenues of heme synthesis regulation. (Medlock A E, et al., 2022)

The biosynthesis of heme offers several technical advantages. It provides a sustainable and scalable method of heme production that can be tailored to specific applications. This approach also minimizes the reliance on traditional extraction methods, which may have limited availability and environmental concerns. Furthermore, biosynthesized heme can be produced with high purity and reduced environmental impact, making it an attractive option for various industries.

Heme Biosynthesis Pathway

Heme biosynthesis involves a highly regulated and intricate pathway that unfolds in several distinct stages. This pathway, also known as porphyrin biosynthesis, commences within the mitochondria and progresses through the cytoplasm. It can be categorized into the following key steps.

Heme Biosynthesis Pathway

How We Can Help

Our company employs advanced synthesis methods, such as enzymatic pathways and fermentation processes, to produce heme with unmatched precision and efficiency. Our biosynthesis of heme offers distinct technical advantages, including scalability, sustainability, and reduced environmental impact, making it a game-changer in the field of biotechnology. We offer a comprehensive suite of services and technologies to facilitate Heme biosynthesis, including:

Customized pathway engineering for optimized Heme production.

Strain development and fermentation process optimization.

Quality control and purification methods to ensure high-purity Heme.

Sustainable production techniques with minimal environmental impact.

Research and development support for tailored Heme applications.

Applicationsof Heme Biosynthesis

Heme biosynthesis opens the door to a wide range of applications, including:

  • Biopharmaceuticals: Production of Heme for hemoglobin-based therapeutics.
  • Food and Beverage: Enhancement of the nutritional profile and color of food products.
  • Agriculture: Improvement of plant growth and stress tolerance.
  • Environmental Remediation: Utilization of Heme for wastewater treatment and bioremediation.
  • Research: Supporting academic and industrial research endeavors in various fields.

CD Biosynsis empowers industries with sustainable, high-quality heme production. Whether you're in biopharmaceuticals, agriculture, or any other field requiring Heme, we have the expertise and technology to meet your needs. Contact us today to explore the boundless possibilities of heme biosynthesis and revolutionize your industry with our innovative solutions.


  1. Medlock, A. E.; et al. New Avenues of Heme Synthesis Regulation. International Journal of Molecular Sciences. 2022, 23(13), 7467.

Please note that all services are for research use only. Not intended for any clinical use.

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