CD Biosynsis is committed to providing a basis for the modification of biosynthetic pathways in natural rubber through high-throughput multi-omics data analysis.
Natural rubber, usually extracted from gum-bearing plants, is an irreplaceable and highly valuable biopolymer. Natural rubber has unique physical properties, including high resilience, impact and abrasion resistance, heat dissipation, and ductility at low temperatures, which are only important for transportation, pharmaceutical, and defense industries. Currently, natural rubber is produced exclusively from rubber trees, and the increasing demand for natural rubber has inspired scientists to explore synthetic biology methods that can replace rubber trees in the production of natural rubber
Figure 1. Model of the natural rubber biosynthetic machinery. (Yamashita S, et al., 2020)
Development of Genetically Engineered Microbial for Natural Rubber Production
The synthesis of natural rubber includes the initiation of rubber molecule formation, the extension of rubber molecule chains, and the termination of rubber molecule synthesis. Each step is regulated by the enzymatic activity of rubber biosynthesis. We are able to construct a gene that encodes an amino acid sequence identical to that of a plant enzyme, which can be optimized for engineered microorganisms.
Regulation of Natural Rubber Biosynthesis
Rubber biosynthesis is regulated by the activity of enzymes involved in rubber biosynthesis, including 3-hydroxy-3-methylglutaryl coenzyme, isopentenyl pyrophosphate isomerase, rubber transferase, etc. We are able to regulate the production of natural rubber by regulating the activity of the above enzymes.
CD Biosynsis can develop tailored tools and customized approaches to harness the power of synthetic biology to drive natural rubber production and meet the needs of customers in a variety of industries.
CD Biosynsis provides the most comprehensive and efficient solutions for synthetic biology workflows. We are committed to helping our customers solve all problems encountered in natural rubber production to advance their applications in a wide range of fields. Each of our deliverables will undergo a rigorous quality inspection test to ensure the reliability and accuracy of the results. If you are interested in our services or have any further questions, please do not hesitate to contact us.