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Protein Design Service

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CD Biosynsis provides customized protein design services for synthetic biology researchers around the world to facilitate their cutting-edge research.

Introduction to Protein Design

Protein design aims to create proteins with enhanced or novel activity, behavior, or other functional properties. As a powerful tool, it may have a profound impact on synthetic biology and may have more rapid and innovative applications. In the near future, protein design, especially computational design, will greatly expand the functional capabilities of synthetic cells.

Figure 1. Landscape of computational design approaches and potential applications in synthetic biology. (Gainza-Cirauqui P & Correia B E., 2018)Figure 1. Landscape of computational design approaches and potential applications in synthetic biology. (Gainza-Cirauqui P & Correia B E., 2018)

Our Capabilities

  • Design of globular proteins
  • Design of membrane proteins
  • Design of single-chain proteins
  • Antibody design
  • Design for affinity
  • Design for specificity
  • Design of structures
  • Functional design

Featured Technologies

  • Computational protein design

    —Search for mutants with desired improved properties.
    —Provided by our experienced team of scientists using our proprietary tools.

  • Automated protein design

    —Objective prediction of protein sequences that may achieve the desired fold.
    —Address problems considered beyond traditional protein engineering.

Service Offering

CD Biosynsis provide tailored solutions and powerful tools to bring diverse synthetic applications and creative ideas to fruition.

De Novo Protein Design

In de novo protein design, the ultimate objective is to identify the appropriate amino acid sequence that best fits the designed topology of protein with the desired functions. We are dedicated to establishing the most exquisite service platform for our clients. Our one-stop services can provide comprehensive technical support to advance our customers' projects.

Rational Protein Design

Rational protein design plays a critical role in understanding protein structure and physical chemistry. It has been widely used in numerous fields, including synthetic biology. Based on the understanding of the target protein's structure and the correlated properties, our professional scientific team can provide our customers with a complete development cycle of rational design.

Semirational Protein Design

As a combination of rational design and directed evolution, semirational protein design has been developed to address the limitations of both methods. Information on protein sequence, structure and function is used together with predictive algorithms to identify target amino acid residues. We provide multiple approaches to bring diverse synthetic applications and creative ideas to fruition.

CD Biosynsis offer a variety of cutting-edge techniques to tailor protein design services for individual customer specifications. We have an experienced scientific team of biologists, bioinformatics, and chemists to help execute innovative designs for unique applications.

We are also available for on-demand customer assistance via email or phone to help you with any problems or concerns you may have. If you are interested in our services or have any specific needs, please feel free to contact us for more details.


  1. Gainza-Cirauqui P & Correia B E. Computational protein design—the next generation tool to expand synthetic biology applications. Current opinion in biotechnology, 2018, 52: 145-152.
  2. Regan L, et al. Protein design: Past, present, and future. Peptide Science, 2015, 104(4): 334-350.

Please note that all services are for research use only. Not intended for any clinical use.

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