Proteasome Inhibitors

Proteasome inhibitors are a class of compounds that have gained significant attention in the field of cancer research and treatment These inhibitors target the proteasome a cellular complex responsible for breaking down proteins in cells By inhibiting this process proteasome inhibitors disrupt the normal protein degradation pathway leading to the accumulation of damaged or misfolded proteins and ultimately triggering cell death This targeted approach has shown promise in the treatment of various types of cancers making proteasome inhibitors a valuable tool in the fight against this devastating disease

Catalog Number	Chemical Name	CAS #	Price
BC-0682	(-)-Epigallocatechin gallate	989-51-5	Online Inquiry
BC-0693	Celastrol	34157-83-0	Online Inquiry
EI-0165	Amastatin hydrochloride	100938-10-1	Online Inquiry
EI-0494	Calpain Inhibitor I, ALLN	110044-82-1	Online Inquiry
EI-0495	Calpain Inhibitor II, ALLM	136632-32-1	Online Inquiry
EI-0513	Carfilzomib	868540-17-4	Online Inquiry
EI-0555	CEP-18770	847499-27-8	Online Inquiry
EI-0621	Clasto-Lactacystin β-lactone	154226-60-5	Online Inquiry
EI-0624	Clioquinol	130-26-7	Online Inquiry
EI-0821	Epoxomicin	134381-21-8	Online Inquiry
EI-0975	Fenbendazole	43210-67-9	Online Inquiry
EI-1311	Lactacystin (Natural)	133343-34-7	Online Inquiry
EI-1416	Marizomib	437742-34-2	Online Inquiry
EI-1503	MLN-9708	1239908-20-3	Online Inquiry
EI-1641	ONX-0914	960374-59-8	Online Inquiry

Application

Proteasome inhibitors have a wide range of applications in both research and medicine In the field of research they are commonly used to study the role of protein degradation in various biological processes By inhibiting the proteasome scientists can better understand how proteins are regulated and degraded which can provide valuable insights into many diseases and conditions

In medicine proteasome inhibitors are used as a targeted therapy for certain types of cancer By blocking the proteasome's function these inhibitors prevent the breakdown of proteins that control cell growth and division leading to the death of cancer cells This approach has shown significant success in treating multiple myeloma and mantle cell lymphoma and research is ongoing to explore their potential in treating other types of cancer

Additionally proteasome inhibitors are being investigated for their potential in treating autoimmune diseases and neurodegenerative disorders By selectively degrading specific proteins involved in these conditions proteasome inhibitors have the potential to slow or halt disease progression and alleviate symptoms

Overall proteasome inhibitors have emerged as a valuable tool in both research and medicine with the potential to make significant contributions to our understanding and treatment of various diseases

Please note that all services are for research use only. Not intended for any clinical use.

Proteasome Inhibitors