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Engineering of Insects as Synthetic Biology Chassis

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CD Biosynsis is committed to working with our customers to develop insects as the next generation of synthetic biology chassis by integrating entomology and synthetic biology. We are successively building a large insect knowledge base to facilitate the development of synthetic biology tools and promote the exploration of the synthetic potential of insects.


Engineering of Insects as Synthetic Biology Chassis

Although synthetic biology is often built on laboratory organisms and well-known species, such as bacteria and fungi, these organisms are sometimes not ideal chassis. Therefore, the development of new chassis capable of exploiting the advanced functions and applications of different species is required to further expand the potential of synthetic biology. As the largest group in the phylum Arthropoda, insects are the most diverse group of animals. They can be found in virtually all environments. With the rapid development of entomology and technologies such as genetic engineering, insects are expected to become the next generation of synthetic biology chassis. Insects will bring new blood into the development of synthetic biology and open up more possibilities for biotechnology, industry, agriculture, biomanufacturing and medical applications.

What We Can Do

CD Biosynsis has extensive experience in developing synthetic biology chassis. Our scientists are committed to deepening their understanding of the physical, chemical, and biological properties of insects to determine their value as synthetic biology chassis. We focus our attention on the development of promising research tools for entomology and powerful enabling technologies for synthetic biology to help our customers broadly expand the potential applications of insects. Our technology platform and toolbox will be continuously updated.

ZFNs TALENs CRISPR-Cas systems Insect expression systems In silico screening and modeling
Gene knock-out (KO) Gene knock-in (KI) Gene knock-down (KD) Insect genome sequencing Insect microinjection
Homology-directed repair (HDR) Insect microinjection Insect ribosomal DNA (rDNA) and ribosomal RNA (rRNA) Insect mitochondrial DNA (mtDNA) Insect microRNAs
Insect transposable elements Insect-based proteins Insect transcription factors Insect pheromones Insect bioreactors

Insect-Based Applications

CD Biosynsis is committed to harnessing the power of synthetic biology to unlock the potential of insect applications across a wide range of industries. At present, silkworm (Bombyx mori), mosquitoes, honeybees, butterflies, moths, fireflies, and Dactylopius coccus are our key concerns. We combine the properties and applications of insects with advanced technologies in synthetic biology to help our customers discover new possibilities for model and non-model insects as the next generation of synthetic biology chassis.

  • Insect-based feeds and fertilizers (e.g., insect meal)
  • Insect-based foods (e.g., insect-derived ingredients)
  • Insect-based useful products (e.g., dyes and silks)
  • Medicinal uses (e.g., vaccine production and disease prevention)
  • Biological control (e.g., insect pest management)

Want to Learn More?

CD Biosynsis has been continuously expanding our synthetic biology toolbox and keeping our knowledge and skills current. We provide full support for our customers' innovations in synthetic biology. If you require any further details, please feel free to contact us and let us know how we can support your new idea or project.


  1. Xu J, et al. Genome editing in insects: current status and challenges. National Science Review, 2019, 6(3): 399.
  2. Mateos Fernández R, et al. Insect pest management in the age of synthetic biology. Plant Biotechnology Journal, 2022, 20(1): 25-36.

Please note that all services are for research use only. Not intended for any clinical use.

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