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Poly (ADP-ribose) Polymerase (PARP) Inhibitors

Poly (ADP-ribose) Polymerase (PARP) Inhibitors

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Poly (ADP-ribose) Polymerase (PARP) Inhibitors

Poly (ADP-ribose) polymerase (PARP) inhibitors are a novel class of pharmaceutical drugs that target the PARP enzymes involved in DNA repair pathways By inhibiting PARP these drugs disrupt the repair mechanisms in cancer cells leading to their selective death This makes PARP inhibitors a promising therapeutic option for the treatment of various cancers particularly those associated with BRCA mutations Our company offers a comprehensive range of highly effective PARP inhibitors that have shown significant clinical benefit in the fight against cancer

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EI-0103 ABT-888 912445-05-7 Online Inquiry
EI-0133 AG-014699 phosphate 459868-92-9 Online Inquiry
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EI-0284 AZD-2461 1174043-16-3 Online Inquiry
EI-0411 BMN-673 1207456-01-6 Online Inquiry
EI-0765 DPQ 129075-73-6 Online Inquiry
EI-0768 DR2313 284028-90-6 Online Inquiry
EI-1216 Iniparib 160003-66-7 Online Inquiry
EI-1218 INO-1001 3544-24-9 Online Inquiry
EI-1429 ME-0328 1445251-22-8 Online Inquiry
EI-1471 MK-4827 1038915-60-4 Online Inquiry


Poly (ADP-ribose) Polymerase (PARP) inhibitors have a wide range of applications in both research and medicine In the field of research PARP inhibitors are commonly used to study DNA repair mechanisms and the role of PARP enzymes in cellular processes By inhibiting PARP researchers can gain valuable insights into the underlying mechanisms of DNA damage and repair which can contribute to the development of new therapies for cancer and other diseases

In medicine PARP inhibitors are primarily used to treat cancers that have a specific DNA repair defect known as homologous recombination deficiency (HRD) These inhibitors work by blocking the activity of PARP enzymes which are necessary for the repair of single-strand DNA breaks In HRD cancers blocking PARP leads to the accumulation of DNA damage ultimately leading to cell death This targeted approach has shown promise in the treatment of breast ovarian and other types of cancer and is shaping the future of precision medicine

PARP inhibitors also have potential applications beyond cancer treatment They are being investigated for their role in neurodegenerative diseases such as Alzheimer's and Parkinson's as well as in cardiovascular diseases Additionally PARP inhibitors are being explored for their potential to enhance the effectiveness of radiation therapy or chemotherapy in cancer treatment

Overall PARP inhibitors are a versatile tool with significant implications for both research and medicine Their ability to target specific DNA repair pathways has opened up new avenues of treatment and research offering hope for improved outcomes and better understanding of various diseases

Please note that all services are for research use only. Not intended for any clinical use.

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