CD Biosynsis is dedicated to helping customers discover and screen new lysine-producing strains and improve existing strains to achieve large-scale lysine fermentation production.
Lysine is an essential amino acid for humans and animals and is widely used in medicine, food, and feed. The synthetic pathways of lysine are the aspartic acid pathway and the α-aminoadipic acid pathway. A variety of bacteria and fungi are capable of producing lysine, with bacteria producing lysine through the diaminoheptanedioic acid metabolic pathway and yeast producing lysine through the metabolic pathway that produces the 2-aminoadipic acid intermediate. Currently, fermentation is the predominant method for lysine production.
Figure 1. The DAP pathway of L-lysine synthesis. (Liu N, et al., 2021)
Based on synthetic biology strategies, we are able to optimize the microbial production process of lysine and maximize the potential of the lysine biosynthesis pathway.
Microbial fermentation is currently at the heart of the lysine production industry. We can develop high-yielding microbial chassis. The following table shows the focus of our current work. Please contact us directly if you have other chassis of interest for lysine production.
|Escherichia coli||Corynebacterium glutamicum||Agaricomycetes||Saccharomyces cerevisiae|
|Candida albicans||Cryptococcus neoformans||Bacillus|
We have developed a strain screening method that combines multiple parameters with the fermentation process, and are able to provide high-throughput screening of high-yielding strains of lysine.
We can help our customers genetically modify engineered lysine strains. For example, overexpression of lysine synthesis-related genes, improvement of gene expression product activity, reduction of branched metabolic flow, etc.
CD Biosynsis can develop tailored tools and customized approaches to harness the power of synthetic biology to drive lysine production and meet the needs of customers in a variety of industries.
CD Biosynsis provides the most comprehensive and efficient solutions for synthetic biology workflows. We are committed to helping our customers solve all problems encountered in lysine production to advance their applications in a wide range of fields. Each of our deliverables will undergo a rigorous quality inspection test to ensure the reliability and accuracy of the results. If you are interested in our services or have any further questions, please do not hesitate to contact us.
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.