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Genome Editing

Genome Editing

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Genome Editing

Genome editing tools are a pinnacle of biotechnological innovation that have revolutionized the field of genetics. These cutting-edge technologies allow scientists to make precise alterations to the DNA sequences of many organisms, including animals, plants, and bacteria. These changes can be minute, such as swapping a single DNA base pair, or they can be significant, such as the addition or deletion of entire genes.

Genome Editing
Catalog Number Product Name Product Size Applications Price
GE0001L Cas9-NLS 400 pmol Random Mutagenesis Online Inquiry
GE0001X Cas9-NLS 2,000 pmol Random Mutagenesis Online Inquiry
GE0002S CD® Cas12a 70 pmol Random Mutagenesis Online Inquiry
GE0002X CD® Cas12a 2,000 pmol Random Mutagenesis Online Inquiry
GE0003S CD® Cas9 Nickase 70 pmol Random Mutagenesis Online Inquiry
GE0003L CD® Cas9 Nickase 400 pmol Random Mutagenesis Online Inquiry
GE0004S CD® Cas9 Nuclease 70 pmol Random Mutagenesis Online Inquiry
GE0004L CD® Cas9 Nuclease 400 pmol Random Mutagenesis Online Inquiry
GE0004X CD® Cas9 Nuclease 2,000 pmol Random Mutagenesis Online Inquiry
GE0005 CRISPR Nuclease mRNA 15 μg Insertion of target sequence into the Cas9-sgRNA constructs. Online Inquiry
GE0006 gRNA Synthesis Kit 20 Reactions Random Mutagenesis Online Inquiry
GE0007S Monarch RNA Cleanup Kit 10 Preps Random Mutagenesis Online Inquiry
GE0007L Monarch RNA Cleanup Kit 100 Preps Random Mutagenesis Online Inquiry
GE0008S sgRNA Synthesis Kit 10 Reactions Random Mutagenesis Online Inquiry
GE0008L sgRNA Synthesis Kit 20 Reactions Random Mutagenesis Online Inquiry
GE0009S SNAP-tagged dCas9 70 pmol Random Mutagenesis Online Inquiry
GE0009L SNAP-tagged dCas9 400 pmol Random Mutagenesis Online Inquiry
GE0010S Staphylococcus aureus Cas9 70 pmol Random Mutagenesis Online Inquiry
GE0010L Staphylococcus aureus Cas9 400 pmol Random Mutagenesis Online Inquiry
GE0011 High-Fidelity DNA Assembly Cloning Kit 10 Reactions Function as a DNA-guided endonuclease. Online Inquiry
GE0012S High-Fidelity DNA Assembly Master Mix 10 Reactions High-fidelity construct generation for CRISPR workflows. Online Inquiry
GE0012L High-Fidelity DNA Assembly Master Mix 50 Reactions High-fidelity construct generation for CRISPR workflows. Online Inquiry
GE0012X High-Fidelity DNA Assembly Master Mix 250 Reactions High-fidelity construct generation for CRISPR workflows. Online Inquiry
GE0013 Genomic Cleavage Detection Kit 25 Reactions Single-tube, isothermal generation of the Cas9-sgRNA constructs. Online Inquiry
GE0014 Mutation Detection Kit 25 Reactions Determination of the targeting efficiency of genome editing. Online Inquiry
GE0015S T7 Endonuclease I 250 Units Function as a DNA endonuclease. Online Inquiry
GE0015L T7 Endonuclease I 1,250 Units Function as a DNA endonuclease. Online Inquiry

Application

Genome editing has evolved into a transformative field, driven by a diverse array of products that enable precise manipulation of genetic material. These products cater to a range of applications, from targeted gene editing within cellular systems to in vitro modifications of DNA. Here's a comprehensive overview of some prominent Genome Editing products:

1.CRISPR-Cas9 Cell Lines:

Purpose: Facilitates efficient and targeted gene editing within cellular systems.
Description: Engineered cell lines expressing the CRISPR-Cas9 system for specific and controlled genomic modifications.

2.sgRNA Synthesis Kit:

Purpose: Allows the production of synthetic guide RNAs (sgRNAs) for guiding Cas9 or other nucleases to target DNA sequences.
Description: Kits providing the necessary reagents for the synthesis of sgRNAs, a crucial component in the CRISPR-Cas system.

3.TALEN Expression Vectors:

Purpose: Enables targeted genome editing through the introduction of customizable Transcription Activator-Like Effector Nucleases (TALENs).
Description: Plasmids or vectors containing TALEN sequences for efficient and programmable genome modifications.

4.ZFN (Zinc Finger Nuclease) Kits:

Purpose: Provides components for using ZFNs, allowing researchers to induce site-specific double-strand breaks for genome engineering.
Description: Kits containing ZFNs for targeted DNA cleavage and subsequent modifications with high precision.

5.CRISPR-Cas12 Cell Lines:

Purpose: Engineered cell lines expressing Cas12 for targeted DNA cleavage with distinct advantages over Cas9.
Description: Allows researchers to leverage the unique features of Cas12 for specific applications in DNA editing.

6.Base Editing Kits:

Purpose: Facilitates base pair modifications without causing double-strand breaks, allowing precise changes in DNA sequences.
Description: Kits for performing base editing, a revolutionary technique for direct conversion of one DNA base pair to another.

7.RNAi Libraries:

Purpose: Collections of siRNAs or shRNAs for targeted gene silencing through RNA interference.
Description: Provides a library of small RNA molecules for researchers to study and modulate gene expression with high specificity.

8.Homologous Recombination Kits:

Purpose: Facilitates the introduction of specific genetic sequences into target genomes through homologous recombination.
Description: Kits enabling researchers to achieve precise genome modifications by promoting recombination events.

9.CRISPR-Cas9 Protein:

Purpose: In vitro genome editing applications using purified Cas9 protein.
Description: Allows researchers to perform precise genome editing outside of living cells for various experimental setups.

Please note that all services are for research use only. Not intended for any clinical use.

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