Synthetic Biology
Flavonoid Strain Engineering

Flavonoid Strain Engineering

Home / Applications / Strain Engineering for others / Flavonoid Strain Engineering
Flavonoid Strain Engineering

Flavonoids are a diverse group of plant secondary metabolites known for their various health benefits. Our company specializes in Flavonoid Strain Engineering, which involves the modification of plant strains to enhance the production of specific flavonoids. By leveraging advanced genetic engineering techniques, we aim to unlock the full potential of flavonoid biosynthesis.

flavonoid synthetic pathway in microbesflavonoid synthetic pathway in microbes (Junjun, W., et al. 2014)

Flavonoid Biosynthesis Technical Roadmap:

  1. Identification of target flavonoids and their biosynthesis pathways: The first step in our biosynthesis roadmap is to identify the specific flavonoids that we aim to produce. We conduct extensive research to understand the biosynthesis pathways of these target flavonoids in plants. By studying the genes and enzymes involved in their production, we gain insights into the genetic modifications required to enhance their synthesis.
  2. Genetic manipulation to enhance flavonoid production in plant strains: Once we have identified the target flavonoids and their biosynthesis pathways, we proceed with genetic manipulation. Using advanced genetic engineering techniques, we introduce specific genetic modifications into plant strains. These modifications can include gene insertions, deletions, or alterations to enhance the expression of enzymes involved in flavonoid production.
  3. Metabolic engineering to optimize biosynthesis pathways for increased yields: In this step, we focus on metabolic engineering to optimize the biosynthesis pathways of flavonoids. We fine-tune the metabolic flux by modulating the expression of key enzymes and regulatory factors. By manipulating the flux through the pathway, we enhance the production of flavonoids and improve their yields.
  4. Fine-tuning of key enzymes and regulatory factors for efficient and sustainable production: To ensure efficient and sustainable production of flavonoids, we further refine the biosynthesis process. We conduct detailed analysis and experimentation to identify the key enzymes and regulatory factors that play crucial roles in flavonoid synthesis. By fine-tuning their expression levels and activity, we achieve higher yields of flavonoids while maintaining the stability and sustainability of the production process.
  5. Validation and optimization of engineered plant strains: Once the genetic and metabolic modifications are implemented, we proceed with the validation and optimization of the engineered plant strains. We evaluate the flavonoid production levels, composition, and bioactivity of the modified strains. This step allows us to assess the success of our engineering efforts and make any necessary adjustments for further improvement.

By following this technical roadmap, we aim to unlock the full potential of flavonoid biosynthesis and revolutionize the production of these valuable plant compounds. Our approach combines advanced genetic engineering and metabolic engineering techniques to maximize flavonoid yields, tailor their profiles, and enhance their bioactivity. The result is a sustainable and efficient method for producing flavonoids with diverse applications in industries such as nutraceuticals, pharmaceuticals, cosmetics, and agriculture.

Key Features:

  • Enhanced Flavonoid Production: Our strain engineering approach maximizes flavonoid yields, allowing for larger-scale production and commercial viability.
  • Tailored Flavonoid Profiles: We have the capability to customize the flavonoid composition of plant strains, creating tailored profiles to meet specific application requirements.
  • Improved Bioactivity: Our engineered strains produce flavonoids with enhanced bioactivity, increasing their potential for various health and industrial applications.

Application Areas We Serve:

Our Flavonoid Strain Engineering service finds applications in various sectors, including:

  • Nutraceuticals and Functional Foods: We enable the production of high-quality flavonoids for dietary supplements and functional food products, catering to the growing demand for natural health-enhancing ingredients.
  • Pharmaceutical Industry: Our engineered strains provide a sustainable source of flavonoids for drug development, offering potential therapeutic benefits for various diseases.
  • Cosmetics and Personal Care: We assist in the production of plant-derived flavonoids for cosmetic formulations, harnessing their antioxidant and anti-inflammatory properties for skincare and haircare applications.
  • Agriculture and Crop Improvement: Our strain engineering expertise can be applied to enhance the flavonoid content of crops for improved crop yield, stress tolerance, and disease resistance.

With our Flavonoid Strain Engineering service, we aim to revolutionize the production and application of flavonoids, unlocking their full potential for diverse industries and improving the well-being of individuals worldwide.

Please note that all services are for research use only. Not intended for any clinical use.

Synthetic Biology Applications

Online Inquiry