Ubiquitin Proteasome Pathway Inhibitors

Ubiquitin-proteasome pathway inhibitors are a class of compounds that regulate the degradation of proteins within cells The ubiquitin-proteasome pathway is a fundamental process that plays a crucial role in maintaining protein homeostasis and regulating various cellular functions These inhibitors work by disrupting the activity of the proteasome the cellular machinery responsible for protein degradation By inhibiting this pathway these compounds can selectively target specific proteins for degradation leading to a modulation of cellular processes The use of ubiquitin-proteasome pathway inhibitors has shown promise in various areas of research including cancer therapy and neurodegenerative diseases making them valuable tools for understanding and potentially treating these conditions

Catalog Number	Chemical Name	CAS #	Price
BC-0665	TZ9	1002789-86-7	Online Inquiry
BC-0682	(-)-Epigallocatechin gallate	989-51-5	Online Inquiry
BC-0693	Celastrol	34157-83-0	Online Inquiry
EI-0022	(±)-Thalidomide	50-35-1	Online Inquiry
EI-0494	Calpain Inhibitor I, ALLN	110044-82-1	Online Inquiry
EI-0495	Calpain Inhibitor II, ALLM	136632-32-1	Online Inquiry
EI-0513	Carfilzomib	868540-17-4	Online Inquiry
EI-0555	CEP-18770	847499-27-8	Online Inquiry
EI-0621	Clasto-Lactacystin β-lactone	154226-60-5	Online Inquiry
EI-0624	Clioquinol	130-26-7	Online Inquiry
EI-0715	DBeQ	177355-84-9	Online Inquiry
EI-0787	Eeyarestatin I	412960-54-4	Online Inquiry
EI-0975	Fenbendazole	43210-67-9	Online Inquiry
EI-1054	Ginkgolic acid C15:1	22910-60-7	Online Inquiry
EI-1158	HBX-41108	924296-39-9	Online Inquiry

Application

The Ubiquitin Proteasome Pathway Inhibitors are essential tools in biomedical research particularly in the field of cancer research These inhibitors are used to study the intricate mechanism of the ubiquitin-proteasome system a crucial pathway responsible for regulating protein degradation in cells By inhibiting this pathway scientists can gain insights into how proteins are degraded and explore potential targets for cancer therapy as aberrations in the ubiquitin-proteasome system are often associated with the development and progression of cancer

Moreover Ubiquitin Proteasome Pathway Inhibitors have also shown promise in the treatment of neurodegenerative diseases such as Parkinson's and Alzheimer's These inhibitors help alleviate the buildup of abnormal proteins such as tau and alpha-synuclein which are hallmark features of these diseases By targeting and inhibiting the ubiquitin-proteasome system researchers aim to develop effective therapies that can slow down or halt the progression of neurodegenerative diseases

In addition to their applications in research and medicine Ubiquitin Proteasome Pathway Inhibitors are also utilized in pharmaceutical drug discovery Studying the effects of these inhibitors on protein degradation pathways can aid in identifying potential drug targets designing novel therapeutic agents and evaluating the efficacy of drug candidates

Overall the use of Ubiquitin Proteasome Pathway Inhibitors enables scientists and researchers to gain a deeper understanding of protein regulation and degradation paving the way for advancements in cancer research neurodegenerative disease treatments and drug discovery

Please note that all services are for research use only. Not intended for any clinical use.

Ubiquitin Proteasome Pathway Inhibitors