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Methionine Strain Engineering

Methionine Strain Engineering

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Methionine Strain Engineering

CD Biosynsis offers comprehensive and advanced strain engineering techniques tailored for methionine production, catering exclusively to research endeavors. We specialize in bioengineering solutions, assisting researchers in optimizing methionine biosynthesis pathways to meet their specific experimental needs.


Methionine, an essential amino acid, holds paramount significance in the realm of biology and biochemistry. This sulfur-containing amino acid plays a pivotal role in protein synthesis and diverse metabolic pathways. As a key component of enzymes and proteins, methionine serves as a fundamental building block for cellular functions across various organisms. Its indispensability in life processes underscores the significance of understanding its biosynthesis and potential applications in scientific research.

Fermentation production of l-methionine by genetically engineered strains. Fig 1. Fermentation production of l-methionine by genetically engineered strains. (Niu K, et al., 2023)

The synthesis of methionine can occur through both biological and chemical pathways. In biological systems, methionine biosynthesis transpires via a multistep enzymatic process, predominantly in microorganisms and plants. Homocysteine, an intermediate in the transsulfuration pathway, serves as the precursor for methionine biosynthesis. In this pathway, the enzyme cystathionine β-synthase catalyzes the conversion of homocysteine to cystathionine, which is further converted to cysteine. Methionine is then synthesized from cysteine in a subsequent series of enzymatic reactions.

Process of Strain Engineering for Methionine

Strain engineering for methionine primarily involves the following steps:

Process of Strain Engineering for Methionine.

Services We Offering

  • Methionine Biosynthesis Pathway Analysis
  • Metabolic Engineering
  • Enzyme Characterization
  • Strain Development and Genetic Engineering
  • Fermentation Process Optimization
  • Methionine Quantification and Analysis

How to Apply for Services

Incorporating our services into your research is a straightforward process:

  • Contact Us. Reach out to our team to discuss your research requirements.
  • Consultation. Collaborate with our experts to tailor a methionine biosynthesis plan.
  • Service Implementation. We will execute the chosen services with precision and efficiency.
  • Results Delivery. Receive high-quality methionine products or research data promptly.
  • Ongoing Support. We offer post-service support for any further inquiries or assistance.

In the realm of methionine biosynthesis, our specialized strain engineering services stand as the ideal partner for research endeavors. CD Biosynsis focuses on precision, sustainability, and scientific rigor. For inquiries or collaborations, please do not hesitate to contact us, and let us help you unlock the potential of methionine biosynthesis in your projects.


  1. Niu, K.; et al. High-level production of l-methionine by dynamic deregulation of metabolism with engineered nonauxotroph Escherichia coli. 2023, 12(2): 492-501.
Please note that all services are for research use only. Not intended for any clinical use.

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