CD Biosynsis is committed to helping customers develop green and high-yield isoprene biosynthesis technologies by modifying the metabolic pathways of strains through genetic engineering and metabolic engineering.
Isoprene is an important C5 platform chemical with a wide range of applications in rubber, food, fragrances, and aviation fuels. The synthesis of isoprene is mainly divided into chemical synthesis and biosynthesis. Although chemical synthesis and technology are improving, with the gradual depletion and non-renewability of oil, the material shortage will become a bottleneck for the industrial production of isoprene. Certain plants and microorganisms are capable of producing isoprene. However, the production of isoprene by plants and microorganisms under natural conditions is less productive and difficult to collect and is susceptible to climate and growth cycles. Therefore, large-scale production of isoprene from plants is not practical. The ability to obtain monomeric isoprene using microbial fermentation, which has the advantages of low cost, high yield, short production cycle, and low pollution, has become a hot research topic in this field in recent years.
Figure 1. Isoprene biosynthesis pathway divided into three modules using key intermediates as the connecting nodes. (Ye L, et al., 2016)
There is a wide variety of wild-type strains that synthesize isoprene, but the yield of isoprene is low and does not meet the production demand. Therefore, our scientists use genetic and metabolic engineering based on a synthetic biology platform to help our customers achieve large-scale production of isoprene.
We are able to use genetic engineering to regulate the metabolic network and metabolic pathways of microbial isoprene.
We are able to use metabolic engineering to construct highly efficient isoprene-producing strains to achieve large-scale production of isoprene.
Microorganisms have the advantages of small size, fast growth, and the ability to utilize renewable substrate resources. Therefore, the use of microbial fermentation to produce isoprene is of great importance. We have successfully used the following microorganisms to produce monomeric isoprene, and if you wish to synthesize isoprene by other microbial chassis, please contact us directly.
|Bacillus subtilis||Rhodobacter sphaeroides||S. cerevisiae||Escherichia coli|
We are able to reconstruct the complete isoprene synthesis pathway in vitro using protein redesign techniques.
We can assist our customers in screening the most suitable carbon, nitrogen, and organic acids for the isoprene fermentation process and help them optimize the fermentation process and fermentation conditions to improve the yield of isoprene.
CD Biosynsis can develop tailored tools and customized approaches to harness the power of synthetic biology to drive isoprene production and meet the needs of customers in a variety of industries.
CD Biosynsis provides the most comprehensive and efficient solutions for synthetic biology workflows. We are committed to helping our customers solve all problems encountered in isoprene production to advance their applications in a wide range of fields. Each of our deliverables will undergo a rigorous quality inspection test to ensure the reliability and accuracy of the results. If you are interested in our services or have any further questions, please do not hesitate to contact us.
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.