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FHL3 Knockout cell line (HCT 116)

Catalog Number: KO39165

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Specifications

Product Information
Product Name FHL3 Knockout cell line (HCT 116)
specification 1*10^6
Storage and transportation Dry ice preservation/T25 live cell transportation.
Cell morphology Epithelioid, adherent cell
Passage ratio 1:2~1:4
species Human
Gene FHL3
Gene ID 2275
Build method Electric rotation method / virus method
Mycoplasma testing Negative
Cultivation system 90%McCOYs 5A+10% FBS
Parental Cell Line HCT 116
Quality Control Genotype: FHL3 Knockout cell line (HCT 116) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name four and a half LIM domains 3provided by HGNC
Also known as SLIM2
Gene Description The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Expression Ubiquitous expression in esophagus (RPKM 21.3), endometrium (RPKM 16.8) and 25 other tissues See more

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