Gene: FHL3
Official Full Name: four and a half LIM domains 3provided by HGNC
Gene Summary: The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17602 | FHL3 Knockout cell line (HeLa) | Human | FHL3 | 1:3~1:6 | Negative | Online Inquiry |
KO17603 | FHL3 Knockout cell line (HEK293) | Human | FHL3 | 1:3~1:6 | Negative | Online Inquiry |
KO17604 | FHL3 Knockout cell line (A549) | Human | FHL3 | 1:3~1:4 | Negative | Online Inquiry |
KO39165 | FHL3 Knockout cell line (HCT 116) | Human | FHL3 | 1:2~1:4 | Negative | Online Inquiry |
FHL3 Gene Knockout Cell Lines are specifically engineered cellular models designed to enable comprehensive studies of the FHL3 gene's biological function and its role in various physiological processes. Utilizing CRISPR-Cas9 gene-editing technology, these cell lines are meticulously crafted to eliminate FHL3 expression, allowing researchers to observe and elucidate the downstream effects of its absence in regulated cellular environments.
The key function of FHL3 Gene Knockout Cell Lines lies in their ability to provide insights into gene function, signaling pathways, and disease mechanisms. By observing phenotypic changes, biochemical alterations, and gene expression profiles post-knockout, scientists can draw significant conclusions about the role of FHL3 in cellular processes, such as cell differentiation, proliferation, and response to external stimuli. This is particularly relevant for studies on metabolic disorders, cardiovascular diseases, or cancer, where FHL3 may play a pivotal role.
The scientific importance of these cell lines extends to both research and clinical applications. In laboratory settings, they facilitate the study of gene function in a variety of biological contexts, essential for understanding key pathways that could lead to the development of therapeutic targets. In clinical research, FHL3 knockout models can serve as a platform for drug development, screen for potential pharmacological agents, and aid in the validation of biomarkers associated with diseases.
One of the standout advantages of our FHL3 Gene Knockout Cell Lines is their high specificity and efficiency of gene editing, ensuring that researchers achieve accurate and reliable results. This uniqueness, combined with rigorous quality control during production, guarantees that our cell lines outperform standard knockdown models that may suffer from incomplete suppression of gene expression.
For researchers and clinicians seeking advanced solutions, FHL3 Gene Knockout Cell Lines represent an invaluable tool to unravel complex biological mechanisms. Our company specializes in high-quality biological products and has a proven track record of reliability and innovation in gene editing technologies, making us a trusted partner in your scientific endeavors. Embrace the potential of targeted research with our FHL3 Gene Knockout Cell Lines and drive your studies towards impactful discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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