DYRK3 Knockout cell line (HCT 116)

Catalog Number: KO06266

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Specifications

Product Information
Product Name	DYRK3 Knockout cell line (HCT 116)
specification	1*10^6
Storage and transportation	Dry ice preservation/T25 live cell transportation.
Cell morphology	Epithelioid, adherent cell
Passage ratio	1:2~1:4
species	Human
Gene	DYRK3
Gene ID	8444
Build method	Electric rotation method / virus method
Mycoplasma testing	Negative
Cultivation system	90%McCOYs 5A+10% FBS
Parental Cell Line	HCT 116
Quality Control	Genotype: DYRK3 Knockout cell line (HCT 116) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	dual specificity tyrosine phosphorylation regulated kinase 3provided by HGNC
Also known as	RED; REDK; DYRK5; hYAK3-2
Gene Description	This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Expression	Broad expression in testis (RPKM 8.5), gall bladder (RPKM 5.7) and 19 other tissues See more

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