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CCDC62 Knockout Cell Lines

Gene: CCDC62

Official Full Name: coiled-coil domain containing 62provided by HGNC

Gene Summary: Enables nuclear estrogen receptor binding activity and nuclear receptor coactivator activity. Involved in cellular response to estradiol stimulus; positive regulation of transcription by RNA polymerase II; and spermatid development. Located in acrosomal vesicle and nucleus. Implicated in spermatogenic failure 67. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24739 CCDC62 Knockout cell line (HCT 116) Human CCDC62 1:2~1:4 Negative Online Inquiry

Background

CCDC62 Gene Knockout Cell Lines are genetically modified cell lines in which the CCDC62 gene has been disrupted using CRISPR-Cas9 technology. This defining feature allows for the specific examination of the gene's function in cellular mechanisms and its role in various biological pathways, particularly those associated with cytoskeletal dynamics and cellular signaling.

The primary function of these knockout cell lines is to facilitate in-depth studies on the implications of CCDC62 absence within the cellular architecture and behavior. The CRISPR-Cas9 approach ensures precise modifications, leading to a complete loss of function of the CCDC62 gene. As researchers utilize these cell lines, they can investigate changes in cellular processes, such as migration, proliferation, and response to stimuli, providing valuable insights into the gene's contribution to health and disease states.

The scientific importance of CCDC62 gene studies lies in its potential associations with various pathological conditions, including cancer and developmental disorders. These knockout cell lines serve as robust models for understanding the gene's role in tumorigenesis and drug response, thereby aiding in the identification of novel therapeutic strategies. In clinical settings, the insights gained from these studies can inform the development of targeted therapies, highlighting the significance of understanding gene functionality in precision medicine.

Compared to alternatives, such as traditional RNA interference methods or other knockout systems, CCDC62 Gene Knockout Cell Lines offer several advantages. Their generation through CRISPR-Cas9 not only allows for high efficiency and specificity but also provides the modified cells with a stable genetic background. This stability ensures reproducibility and reliability, critical components in any research setting.

Researchers and clinicians will find great value in these cell lines, as they streamline experimental designs for functional genomic studies while providing a clear pathway to decipher the biological roles and pathways influenced by CCDC62. Ultimately, the ability to produce and utilize these knockout cell lines positions our company at the forefront of genetic research tools, showcasing our commitment to supplying advanced solutions for the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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