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RPGR Knockout cell line (A549)

Catalog Number: KO35584

Price: Online Inquiry

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Specifications

Product Information
Product Name RPGR Knockout cell line (A549)
specification 1*10^6
Storage and transportation Dry ice preservation/T25 live cell transportation.
Cell morphology Epithelioid, adherent cell
Passage ratio 1:3~1:4
species Human
Gene RPGR
Gene ID 6103
Build method Electric rotation method / virus method
Mycoplasma testing Negative
Cultivation system 90% F12K+10% FBS
Parental Cell Line A549
Quality Control Genotype: RPGR Knockout cell line (A549) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name retinitis pigmentosa GTPase regulatorprovided by HGNC
Also known as CRD; RP3; COD1; PCDX; RP15; XLRP3; orf15; CORDX1
Gene Description This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined. [provided by RefSeq, Dec 2008]
Expression Ubiquitous expression in testis (RPKM 2.6), lung (RPKM 2.3) and 25 other tissues See more

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