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MTRFR Knockout cell line (HEK293)

Catalog Number: KO15967

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Specifications

Product Information
Product Name MTRFR Knockout cell line (HEK293)
specification 1*10^6
Storage and transportation Dry ice preservation/T25 live cell transportation.
Cell morphology Epithelioid, adherent cell
Passage ratio 1:3~1:6
species Human
Gene MTRFR
Gene ID 91574
Build method Electric rotation method / virus method
Mycoplasma testing Negative
Cultivation system 90%DMEM+10% FBS
Parental Cell Line HEK293
Quality Control Genotype: MTRFR Knockout cell line (HEK293) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name mitochondrial translation release factor in rescueprovided by HGNC
Also known as SPG55; COXPD7; mtRF-R; C12orf65
Gene Description This nuclear gene encodes a mitochondrial matrix protein that appears to contribute to peptide chain termination in the mitochondrial translation machinery. Two different 1 bp deletions (resulting in the same premature stop codon)result in decreased mitochondrial translation, decreased levels of oxidative phosphorylation complexes and encepthalomyopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Expression Ubiquitous expression in ovary (RPKM 3.7), testis (RPKM 3.5) and 25 other tissues See more

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