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hMX2 Knockout Cell Lines

Gene: HMX2

Official Full Name: H6 family homeobox 2provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing this gene have been associated with inner ear malformations, vestibular dysfunction, and hearing loss. [provided by RefSeq, Aug 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
GP04715 hMX2 gRNA1 KO plasmidhMX2 gRNA2 KO plasmidhMX2 gRNA3 KO plasmid hMX2 $850
GP07358 hMX2 gRNA1 KO plasmidhMX2 gRNA2 KO plasmidhMX2 gRNA3 KO plasmid hMX2 $850

Background

HMX2 Gene Knockout Cell Lines are specially engineered cellular models that have been meticulously designed to lack the HMX2 gene, an important transcription factor involved in various developmental processes and cellular functions. These cell lines provide researchers with a valuable tool to study the impact of HMX2 loss on cellular behavior, gene expression, and signaling pathways. By utilizing CRISPR-Cas9 technology, HMX2 Gene Knockout Cell Lines exhibit a targeted disruption of the gene, ensuring high specificity and efficiency in gene editing.

The functionality of these cell lines allows for the investigation of HMX2's role in myriad biological contexts, including neurodevelopment, as well as the regulation of the epithelial-mesenchymal transition, a critical process in cancer metastasis. By employing these knockout models, researchers can dissect molecular mechanisms at play in both normal physiology and disease states, thereby paving the way for novel therapeutic interventions.

The scientific importance of HMX2 Gene Knockout Cell Lines extends to a wide range of applications in research, including developmental biology, cancer biology, and regenerative medicine. These lines are indispensable for functional genomics studies, offering insights that can lead to breakthroughs in understanding gene-environment interactions and disease etiology.

What sets HMX2 Gene Knockout Cell Lines apart from alternative models is their high fidelity in gene disruption, as well as their optimized growth conditions tailored for various experimental platforms. Researchers benefit from the rapid generation of knockout phenotypes while minimizing off-target effects commonly associated with other gene-editing methods.

The availability of these cell lines can significantly accelerate research timelines, enabling clinical and preclinical studies that strive to elucidate the role of HMX2 in health and disease. By choosing our HMX2 Gene Knockout Cell Lines, users gain access to high-quality, rigorously characterized models developed by a team of experts in molecular biology and genetic engineering. Our commitment to scientific excellence ensures that our products consistently meet the needs of the global scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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