ERCC8 Knockout cell line (A549)

Catalog Number: KO38537

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Specifications

Product Information
Product Name	ERCC8 Knockout cell line (A549)
specification	1*10^6
Storage and transportation	Dry ice preservation/T25 live cell transportation.
Cell morphology	Epithelioid, adherent cell
Passage ratio	1:3~1:4
species	Human
Gene	ERCC8
Gene ID	1161
Build method	Electric rotation method / virus method
Mycoplasma testing	Negative
Cultivation system	90% F12K+10% FBS
Parental Cell Line	A549
Quality Control	Genotype: ERCC8 Knockout cell line (A549) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	ERCC excision repair 8, CSA ubiquitin ligase complex subunitprovided by HGNC
Also known as	CSA; CKN1; UVSS2
Gene Description	This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014]
Expression	Ubiquitous expression in testis (RPKM 4.1), thyroid (RPKM 3.2) and 25 other tissues See more

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