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EGF Knockout cell line (A549)

Catalog Number: KO11314

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Specifications

Product Information
Product Name EGF Knockout cell line (A549)
specification 1*10^6
Storage and transportation Dry ice preservation/T25 live cell transportation.
Cell morphology Epithelioid, adherent cell
Passage ratio 1:3~1:4
species Human
Gene EGF
Gene ID 1950
Build method Electric rotation method / virus method
Mycoplasma testing Negative
Cultivation system 90% F12K+10% FBS
Parental Cell Line A549
Quality Control Genotype: EGF Knockout cell line (A549) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name epidermal growth factorprovided by HGNC
Also known as URG; HOMG4
Gene Description This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Expression Biased expression in kidney (RPKM 47.7), pancreas (RPKM 9.8) and 1 other tissue See more

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