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COL4A6 Knockout cell line (A549)

Catalog Number: KO10404

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Specifications

Product Information
Product Name COL4A6 Knockout cell line (A549)
specification 1*10^6
Storage and transportation Dry ice preservation/T25 live cell transportation.
Cell morphology Epithelioid, adherent cell
Passage ratio 1:3~1:4
species Human
Gene COL4A6
Gene ID 1288
Build method Electric rotation method / virus method
Mycoplasma testing Negative
Cultivation system 90% F12K+10% FBS
Parental Cell Line A549
Quality Control Genotype: COL4A6 Knockout cell line (A549) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name collagen type IV alpha 6 chainprovided by HGNC
Also known as DFNX6; DELXq22.3; CXDELq22.3
Gene Description This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Expression Broad expression in endometrium (RPKM 9.0), gall bladder (RPKM 7.4) and 16 other tissues See more

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