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ZNF853 Knockout Cell Lines

Gene: ZNF853

Official Full Name: zinc finger protein 853provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11928 ZNF853 Knockout cell line (HEK293) Human ZNF853 1:3~1:6 Negative Online Inquiry
KO11929 ZNF853 Knockout cell line (A549) Human ZNF853 1:3~1:4 Negative Online Inquiry

Background

ZNF853 Gene Knockout Cell Lines represent a state-of-the-art biological tool designed to facilitate the exploration of gene function and regulation in cellular contexts. These cell lines have been meticulously engineered through CRISPR-Cas9 technology to achieve a precise deletion of the ZNF853 gene, a member of the zinc-finger proteins known for their roles in transcription regulation and chromatin remodeling. The knockout of ZNF853 allows researchers to investigate its contributions to various cellular processes, including cell proliferation, differentiation, and response to stressors.

The primary function of the ZNF853 knockout cell lines is to serve as a reliable experimental platform to elucidate the biological role of the ZNF853 gene. By employing these cell lines, researchers can assess changes in gene expression, signaling pathways, and even phenotypic outcomes that arise from the loss of this critical transcription factor. This knockout model is particularly valuable in studies focused on cancer biology, developmental biology, and neurobiology, where ZNF853 has been implicated.

In terms of scientific importance, the ZNF853 Gene Knockout Cell Lines facilitate groundbreaking research by providing insights into gene functions that may be disrupted in various diseases. Furthermore, they offer a critical resource for drug development and therapeutic strategies targeting transcriptional dysregulation.

What sets our ZNF853 knockout cell lines apart from other available models is their superior specificity and consistency. Each cell line undergoes rigorous validation for the complete loss of the ZNF853 protein and is subjected to comprehensive characterization to ensure reliable performance in downstream applications. This commitment to quality empowers researchers to achieve reproducible results while minimizing experimental variability.

By incorporating ZNF853 gene knockout cell lines into their research, scientists can uncover novel therapeutic targets and advance the understanding of complex biological systems. Our extensive experience in the field of gene editing and our dedication to providing high-quality biological products position us as a trusted partner in your research endeavors. Consider integrating our ZNF853 Gene Knockout Cell Lines to unlock new insights and advance your work effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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