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ZNF84 Knockout Cell Lines

Gene: ZNF84

Official Full Name: zinc finger protein 84provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34641 ZNF84 Knockout cell line (HeLa) Human ZNF84 1:3~1:6 Negative Online Inquiry
KO34642 ZNF84 Knockout cell line (HCT 116) Human ZNF84 1:2~1:4 Negative Online Inquiry
KO34643 ZNF84 Knockout cell line (HEK293) Human ZNF84 1:3~1:6 Negative Online Inquiry
KO34644 ZNF84 Knockout cell line (A549) Human ZNF84 1:3~1:4 Negative Online Inquiry

Background

ZNF84 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to lack the ZNF84 gene, a critical component involved in various biological pathways, including transcriptional regulation and cellular response to stress. This specialized cell line serves as a powerful tool for researchers studying gene function, disease mechanisms, and therapeutic targets.

The core functionality of ZNF84 Gene Knockout Cell Lines stems from targeted gene disruption techniques, such as CRISPR-Cas9 or traditional homologous recombination. By precisely knocking out the ZNF84 gene, researchers can observe resultant phenotypic changes that highlight the gene's role in cell signaling, differentiation, and apoptosis. This not only facilitates a deeper understanding of ZNF84's biological significance but also aids in deciphering its potential involvement in pathological conditions such as cancer or neurodegenerative diseases.

The scientific importance of ZNF84 Gene Knockout Cell Lines is underscored by their applications in both fundamental and applied research. In basic studies, these cells can be used to unravel the molecular pathways regulated by ZNF84, while in clinical settings, they have the potential to drive drug discovery efforts by serving as platforms for screening novel therapeutics aimed at modulating gene activity.

Compared to alternative cell lines, ZNF84 Gene Knockout Cell Lines stand out due to their specificity and the precision with which they have been developed. These models are often optimized for high-throughput screening and are compatible with various assays, making them versatile in experimental designs. Furthermore, their use minimizes the variability and noise that can confound results when using wild-type cell lines.

For researchers and clinicians alike, the ZNF84 Gene Knockout Cell Lines represent a valuable resource for advancing scientific inquiry and therapeutic interventions. Their ability to illuminate gene function and support drug development initiatives is crucial in an era that increasingly values targeted and personalized medicine.

With a commitment to excellence in genetic engineering and product development, our company leverages cutting-edge technology and extensive expertise to provide high-quality biological products that empower the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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