Gene: ZNF808
Official Full Name: zinc finger protein 808provided by HGNC
Gene Summary: Enables transcription cis-regulatory region binding activity. Involved in cell differentiation; negative regulation of gene expression; and pancreas development. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO11959 | ZNF808 Knockout cell line (HeLa) | Human | ZNF808 | 1:3~1:6 | Negative | Online Inquiry |
KO11960 | ZNF808 Knockout cell line (HCT 116) | Human | ZNF808 | 1:2~1:4 | Negative | Online Inquiry |
KO11961 | ZNF808 Knockout cell line (HEK293) | Human | ZNF808 | 1:3~1:6 | Negative | Online Inquiry |
ZNF808 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to study the function of the ZNF808 gene, which encodes for a zinc finger protein implicated in various biological processes, including gene regulation and cellular differentiation. By employing CRISPR-Cas9 technology, these cell lines feature a precise knockout of the ZNF808 gene, enabling researchers to investigate the gene’s role in both normal physiology and disease states.
The primary function of the ZNF808 Gene Knockout Cell Lines is to provide a controlled environment for examining the phenotypic consequences of ZNF808 gene ablation. This includes analyzing alterations in gene expression patterns, signaling pathways, and cellular behavior such as proliferation, apoptosis, and differentiation. The inherent flexibility of these knockout models allows researchers to employ a variety of downstream applications, including functional assays, transcriptomic studies, and proteomic profiling to generate insights into the biological roles of ZNF808.
The scientific importance of ZNF808 Gene Knockout Cell Lines lies in their potential applications within both basic research and translational medicine. Understanding the interactions and pathways regulated by ZNF808 can shed light on its involvement in disorders like cancer, neurodegenerative diseases, and other pathologies. Furthermore, as gene therapies continue to advance, these models serve as a critical testing ground for validating approaches aimed at correcting genetic defects or modulating gene expression.
Compared to standard cell lines, the ZNF808 Gene Knockout Cell Lines offer unique advantages, including the elimination of confounding gene expression and the ability to model targeted gene disruptions that are relevant in vivo. This specificity enhances the reliability of experimental outcomes, making them more applicable to real-world scenarios. Additionally, the use of CRISPR-Cas9 technology ensures high efficiency and precision, yielding more reproducible and interpretable results than traditional knockout methods.
Researchers and clinicians seeking to uncover the intricate details of gene function will find the value of ZNF808 Gene Knockout Cell Lines to be unmatched. These models not only facilitate cutting-edge research but also hold promise for impactful clinical applications, particularly in developing novel therapeutic strategies.
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Please note that all services are for research use only. Not intended for any clinical use.
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