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ZNF789 Knockout Cell Lines

Gene: ZNF789

Official Full Name: zinc finger protein 789provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11976 ZNF789 Knockout cell line (HeLa) Human ZNF789 1:3~1:6 Negative Online Inquiry
KO11977 ZNF789 Knockout cell line (HCT 116) Human ZNF789 1:2~1:4 Negative Online Inquiry
KO11978 ZNF789 Knockout cell line (HEK293) Human ZNF789 1:3~1:6 Negative Online Inquiry
KO11979 ZNF789 Knockout cell line (A549) Human ZNF789 1:3~1:4 Negative Online Inquiry

Background

ZNF789 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to silence the ZNF789 gene, which is implicated in various biological processes, including cellular differentiation and gene regulation. These knockout cell lines are essential tools for researchers aiming to investigate the physiological functions of ZNF789 and its role in disease mechanisms, particularly in cancer and genetic disorders where aberrant expression or mutation of this gene has been observed.

The key function of ZNF789 knockout cell lines lies in their ability to facilitate the study of gene function through a loss-of-function approach. By creating a cellular environment devoid of ZNF789 expression, researchers can elucidate the gene's contributions to cellular processes such as proliferation, apoptosis, and signaling pathways. The mechanism of action involves targeted gene editing techniques, such as CRISPR/Cas9 or RNA interference, ensuring complete ablation of ZNF789 activity, which in turn provides clear insights into its biological roles.

The scientific importance of ZNF789 knockout cell lines extends to their applications in both basic research and clinical settings. In research, these cell lines serve as model systems for assessing drug responses, exploring gene-environment interactions, and delineating pathways involved in disease progression. Clinically, they can contribute to the identification of potential therapeutic targets and biomarkers, particularly in oncology and regenerative medicine.

Compared to alternative models, ZNF789 knockout cell lines offer unparalleled specificity and reliability. Traditional methods, such as RNA interference or overexpression systems, may not fully recapitulate gene function, often leading to ambiguous results. Our knockout lines, on the other hand, provide a definitive approach that eliminates confounding variables associated with incomplete gene silencing.

For researchers and clinicians, these cell lines represent a vital asset for advancing our understanding of gene function and disease etiology. They empower investigations into ZNF789’s role in critical biological pathways, thus enhancing the potential for innovative therapeutic development.

At [Company Name], we specialize in providing high-quality genetic tools that empower scientific discovery and innovation. Our commitment to rigorous quality control and comprehensive technical support ensures that researchers can confidently rely on our ZNF789 knockout cell lines to drive their research forward.

Please note that all services are for research use only. Not intended for any clinical use.

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