Gene: ZNF784
Official Full Name: zinc finger protein 784provided by HGNC
Gene Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23607 | ZNF784 Knockout cell line (HeLa) | Human | ZNF784 | 1:3~1:6 | Negative | Online Inquiry |
KO23608 | ZNF784 Knockout cell line (HCT 116) | Human | ZNF784 | 1:2~1:4 | Negative | Online Inquiry |
KO23609 | ZNF784 Knockout cell line (HEK293) | Human | ZNF784 | 1:3~1:6 | Negative | Online Inquiry |
KO23610 | ZNF784 Knockout cell line (A549) | Human | ZNF784 | 1:3~1:4 | Negative | Online Inquiry |
ZNF784 Gene Knockout Cell Lines are specifically engineered cellular models that enable researchers to study the biological implications of the ZNF784 gene by disrupting its normal function. This gene encodes a zinc finger protein believed to play significant roles in transcriptional regulation, cellular differentiation, and development. By creating knockout variants of these cell lines, researchers can effectively investigate the consequences of ZNF784 loss-of-function, thereby shedding light on its potential involvement in various diseases, including some cancers and neurodevelopmental disorders.
The primary mechanism of action involves the use of advanced gene editing technologies, such as CRISPR-Cas9, which introduces targeted mutations, leading to a complete ablation of ZNF784 expression. This allows for a comprehensive analysis of gene interactions, signaling pathways, and phenotypic manifestations in a controlled laboratory setting. Additionally, these knockout cell lines serve as a pivotal tool in drug discovery processes, enabling researchers to screen for compounds that may selectively modulate or compensate for the loss of ZNF784 function.
The scientific importance of ZNF784 Gene Knockout Cell Lines lies in their applications across fundamental research and translational studies. They provide invaluable insight into gene function studies, elucidate disease mechanisms, and act as preclinical models for evaluating therapeutic strategies. Compared to alternative models, such as transient transfection or overexpression systems, these knockout lines offer a stable and reproducible system to observe long-term effects that would more accurately reflect physiological conditions.
For researchers and clinicians focusing on genetic studies, cellular responses, or pharmacological interventions, ZNF784 Gene Knockout Cell Lines present significant advantages. They facilitate a more precise dissection of complex genetic interactions and contribute towards the identification of potential biomarkers or therapeutic targets in diseases associated with ZNF784 dysregulation.
At [Company Name], we pride ourselves on our expertise in developing high-quality biological products that empower advancements in life science research. Our ZNF784 Gene Knockout Cell Lines are manufactured following stringent quality control measures, ensuring they meet the highest standards for reliability and performance, and positioning our customers at the forefront of genetic research.
Please note that all services are for research use only. Not intended for any clinical use.
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