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ZNF780A Knockout Cell Lines

Gene: ZNF780A

Official Full Name: zinc finger protein 780Aprovided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11992 ZNF780A Knockout cell line (HeLa) Human ZNF780A 1:3~1:6 Negative Online Inquiry
KO11993 ZNF780A Knockout cell line (HCT 116) Human ZNF780A 1:2~1:4 Negative Online Inquiry
KO11994 ZNF780A Knockout cell line (HEK293) Human ZNF780A 1:3~1:6 Negative Online Inquiry
KO11995 ZNF780A Knockout cell line (A549) Human ZNF780A 1:3~1:4 Negative Online Inquiry

Background

ZNF780A Gene Knockout Cell Lines are genetically engineered cell models designed to provide insights into the function of the ZNF780A gene, which is implicated in various biological processes, including chromatin remodeling and transcriptional regulation. These knockout models effectively eliminate the expression of ZNF780A, allowing researchers to investigate the resultant phenotypic alterations and underlying molecular mechanisms.

The primary function of ZNF780A Gene Knockout Cell Lines lies in their ability to serve as a powerful tool for studying gene functionality and its role in cellular pathways. The knockout is achieved through CRISPR/Cas9 technology, which introduces targeted double-strand breaks in the genomic DNA, leading to the disruption of the gene's reading frame. Consequently, researchers can assess the biological impact of ZNF780A loss-of-function on a variety of cellular processes, such as proliferation, differentiation, and response to external stimuli.

The scientific importance of these knockout cell lines resonates in both research and clinical contexts. They are invaluable for elucidating the role of ZNF780A in cancer biology, neurological disorders, and metabolic conditions, offering insights that could lead to novel therapeutic strategies. Additionally, they can help identify potential biomarkers for disease states, enhancing the understanding of complex genetic interactions.

Compared to alternative models, such as overexpression systems or wild-type cell lines, ZNF780A Gene Knockout Cell Lines offer a more definitive analysis of gene function through loss-of-function studies. Their design ensures reproducibility and consistency, yielding reliable data that can be translated into broader biological contexts.

Researchers and clinicians stand to benefit immensely from the use of these knockout cell lines. The ability to manipulate and study the specific effects of ZNF780A in the cellular environment aids in the development of targeted therapies and personalized medicine approaches. Moreover, the accessibility of these models empowers teams to accelerate their research timelines and improve the quality of their findings.

Our company prides itself on delivering high-quality biological products backed by a team of experts in genetics and molecular biology. With a commitment to advancing research innovations, we provide essential tools that contribute to the growing fields of genomics and biotechnology.

Please note that all services are for research use only. Not intended for any clinical use.

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