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ZNF750 Knockout Cell Lines

Gene: ZNF750

Official Full Name: zinc finger protein 750provided by HGNC

Gene Summary: This gene encodes a protein with a nuclear localization site and a C2H2 zinc finger domain. Mutations in this gene have been associated with seborrhea-like dermatitis with psoriasiform elements. [provided by RefSeq, Jul 2008]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00936 ZNF750 Knockout cell line(KYSE-30) Human ZNF750 1:2~1:4 Negative Online Inquiry

Background

ZNF750 Gene Knockout Cell Lines are specialized cellular models in which the ZNF750 gene has been inactivated through targeted gene editing techniques. ZNF750 (Zinc Finger Protein 750) is a transcription factor that plays a crucial role in cell differentiation, particularly in keratinocyte biology and epithelial tissue development. The knockout of this gene allows researchers to explore its role in various biological processes, including cellular proliferation, apoptosis, and the maintenance of specific cellular phenotypes.

The key mechanism by which ZNF750 gene knockout cell lines function revolves around the absence of the ZNF750 protein, which disrupts normal regulatory pathways involved in gene expression and cellular signaling. This disruption serves as a valuable tool for studying the molecular mechanisms mediating skin development, cancer biology, and other epithelial-related diseases. Researchers utilize these cell lines to investigate the functional consequences of ZNF750 loss in vitro, providing insights that can influence therapeutic strategies and enhance our understanding of pathophysiology.

The scientific importance of ZNF750 knockout cell lines extends to both basic research and clinical applications. In oncology, for instance, examining the role of ZNF750 may lead to novel cancer treatments that better target tumor genome stability or stem cell properties. In dermatological research, understanding how ZNF750 contributes to keratinocyte function can enhance wound healing protocols or psoriasis therapies.

Compared to traditional cell lines or models lacking specific genetic modifications, ZNF750 knockout cell lines provide more precise experimental contexts, ensuring reproducibility and specificity in experimental design. Additionally, these cell lines are generated in-line with the latest CRISPR-Cas9 and genetic engineering techniques, offering researchers advanced reliability in the attainment of desired genetic alterations.

For researchers and clinicians aiming to dissect intricate pathways related to the ZNF750 gene, our ZNF750 Gene Knockout Cell Lines present a unique opportunity. By incorporating these cell lines into their studies, users can unlock meaningful insights that bridge fundamental biology with translational applications. Our company stands at the forefront of genetic technologies, committed to delivering high-quality biological products that empower researchers to advance their scientific endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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