Gene: ZNF74
Official Full Name: zinc finger protein 74provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in actin cytoskeleton and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34664 | ZNF74 Knockout cell line (HeLa) | Human | ZNF74 | 1:3~1:6 | Negative | Online Inquiry |
KO34665 | ZNF74 Knockout cell line (HCT 116) | Human | ZNF74 | 1:2~1:4 | Negative | Online Inquiry |
KO34666 | ZNF74 Knockout cell line (HEK293) | Human | ZNF74 | 1:3~1:6 | Negative | Online Inquiry |
KO34667 | ZNF74 Knockout cell line (A549) | Human | ZNF74 | 1:3~1:4 | Negative | Online Inquiry |
ZNF74 Gene Knockout Cell Lines represent a groundbreaking advancement in the field of genetic research and cellular biology. These cell lines have been specifically engineered to lack the ZNF74 gene, known to be implicated in various biological processes, including gene expression regulation and cellular differentiation. By creating knockout models, researchers can effectively study the functional role of ZNF74 within cellular pathways, elucidating its impact on cellular behavior and potential contributions to disease mechanisms.
The primary mechanism of action involves the targeted deletion of the ZNF74 gene using CRISPR-Cas9 technology, a precise and efficient method for genome editing. This allows for the investigation of gene-gene interactions and the downstream effects of ZNF74 absence on cellular physiology. Researchers utilizing these cell lines can gain insights into oncogenic pathways or metabolic alterations that showcase the importance of ZNF74 in both health and disease.
The scientific importance of ZNF74 Gene Knockout Cell Lines extends to a wide array of applications ranging from basic research to therapeutic developments. For instance, they provide vital tools for drug screening assays, enabling the identification of potential therapeutic agents that may compensate for the loss of ZNF74 function. In clinical settings, understanding the role of ZNF74 can contribute to the development of targeted therapies for diseases where this gene is implicated.
Among the advantages of our ZNF74 knockout cell lines is their validated performance in various experimental conditions, ensuring researchers can replicate results reliably. Compared to alternative models, our product offers comprehensive support and detailed characterization, providing users with the confidence needed to drive their projects forward.
In summary, ZNF74 Gene Knockout Cell Lines stand out as an invaluable resource for advancing scientific knowledge and therapeutic strategies. Our company's expertise lies in the development and validation of cutting-edge biological products designed to facilitate groundbreaking research, empowering scientists and clinicians to explore new frontiers in gene function and disease mechanisms.
Please note that all services are for research use only. Not intended for any clinical use.
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