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ZNF678 Knockout Cell Lines

Gene: ZNF678

Official Full Name: zinc finger protein 678provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12069 ZNF678 Knockout cell line (HeLa) Human ZNF678 1:3~1:6 Negative Online Inquiry
KO12070 ZNF678 Knockout cell line (HCT 116) Human ZNF678 1:2~1:4 Negative Online Inquiry
KO12071 ZNF678 Knockout cell line (HEK293) Human ZNF678 1:3~1:6 Negative Online Inquiry
KO12072 ZNF678 Knockout cell line (A549) Human ZNF678 1:3~1:4 Negative Online Inquiry

Background

ZNF678 Gene Knockout Cell Lines are genetically engineered cells specifically designed to facilitate the study of the ZNF678 gene, which plays a significant role in various biological processes, including gene regulation and cellular development. By utilizing CRISPR-Cas9 technology, these cell lines have undergone a targeted disruption of the ZNF678 gene, allowing researchers to investigate the downstream effects of its absence on cellular functions and gene expression profiles.

The key mechanism of these knockout cell lines hinges on their ability to simulate ZNF678 dysfunction, offering insights into its involvement in critical pathways such as oncogenesis, differentiation, and cell cycle regulation. By studying these alterations, scientists can better understand the functional consequences of ZNF678 loss in models of disease, ranging from cancer to genetic disorders.

The scientific importance of ZNF678 knockout cell lines lies in their applications in both research and clinical settings. They serve as invaluable tools for the exploration of gene function and for the potential identification of therapeutic targets. Furthermore, these cell lines can aid in drug discovery processes, providing a robust platform for testing the efficacy and specificity of novel treatments aimed at conditions linked to aberrant ZNF678 activity.

One of the distinct advantages of using ZNF678 Gene Knockout Cell Lines is their high reproducibility and consistency, compared to traditional methods of gene inactivation, such as RNA interference. This ensures that researchers can confidently interpret their results, leading to more reliable conclusions that enhance the robustness of their studies.

Moreover, these cell lines are an essential asset for both academic and industrial researchers looking to advance their understanding in the field of gene regulation and molecular biology. With a focus on quality and support, our company provides not only these knockout models but also expert guidance on their applications and integration into research workflows.

In conclusion, ZNF678 Gene Knockout Cell Lines are a powerful tool for scientists aiming to dissect the complexities of gene function and regulation, supported by the expertise and commitment of our team to advance biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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