Gene: ZNF649
Official Full Name: zinc finger protein 649provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of osteoblast differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of DNA-templated transcription. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12098 | ZNF649 Knockout cell line (HCT 116) | Human | ZNF649 | 1:2~1:4 | Negative | Online Inquiry |
KO12099 | ZNF649 Knockout cell line (HEK293) | Human | ZNF649 | 1:3~1:6 | Negative | Online Inquiry |
ZNF649 Gene Knockout Cell Lines are specialized cellular models engineered to exhibit a targeted disruption of the ZNF649 gene, a critical player in various cellular processes, including gene regulation and cell differentiation. These knockout cell lines allow for the analysis of ZNF649 function by eliminating its expression, thereby providing an invaluable tool for studying gene function and the molecular mechanisms underlying diseases.
The primary mechanism of action relies on CRISPR-Cas9 technology, which precisely introduces double-strand breaks in the target gene's DNA, leading to its disruption through cellular repair processes. This knockout subsequently affects the expression of downstream genes and cellular pathways, allowing researchers to dissect ZNF649's role in biological processes such as embryonic development, cancer progression, and other pathophysiological conditions.
Within research and clinical settings, ZNF649 Gene Knockout Cell Lines hold significant importance. They offer a platform for drug discovery and development by enabling the identification of novel therapeutic targets associated with diseases wherein ZNF649 is implicated. Additionally, these models provide critical insights into gene interactions and functional genomics, promoting advancements in personalized medicine and targeted therapies.
What sets our ZNF649 Gene Knockout Cell Lines apart from alternatives in the market is their comprehensive validation and characterization, ensuring reliability in experimental outcomes. Each cell line undergoes rigorous quality control, and pertinent data regarding genotype, phenotype, and functional assays are provided, enhancing experimental reproducibility and integrity.
For researchers and clinicians aiming to advance their understanding of gene function and disease mechanisms, the ZNF649 Gene Knockout Cell Lines represent a powerful and versatile resource. Their use can accelerate research timelines and enhance the accuracy of experimental data, leading to greater breakthroughs in the field. As a leader in providing high-quality biological products, our company is committed to empowering scientific discovery and innovation, backed by extensive expertise in gene editing and cellular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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