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ZNF624 Knockout Cell Lines

Gene: ZNF624

Official Full Name: zinc finger protein 624provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12102 ZNF624 Knockout cell line (HeLa) Human ZNF624 1:3~1:6 Negative Online Inquiry
KO12103 ZNF624 Knockout cell line (HCT 116) Human ZNF624 1:2~1:4 Negative Online Inquiry
KO12104 ZNF624 Knockout cell line (HEK293) Human ZNF624 1:3~1:6 Negative Online Inquiry
KO12105 ZNF624 Knockout cell line (A549) Human ZNF624 1:3~1:4 Negative Online Inquiry

Background

ZNF624 Gene Knockout Cell Lines represent a groundbreaking biological tool designed for advanced genetic research and therapeutic exploration. These cell lines have been engineered to exhibit a complete knockout of the ZNF624 gene, which encodes a zinc-finger protein implicated in various cellular processes, including proliferation and differentiation. By removing this gene’s expression, researchers can investigate the cellular pathways influenced by ZNF624, thereby elucidating its role in disease mechanisms such as cancer and developmental disorders.

The key mechanism underlying these knockout cell lines involves CRISPR-Cas9 technology, a precise gene-editing tool that allows for targeted modifications within the genome. By employing this method, scientists can create stable cell lines devoid of the ZNF624 protein, enabling the study of cellular responses and the identification of downstream effects that could lead to new therapeutic strategies. This precision enhances reproducibility and allows for more robust experimental designs in both in vitro and in vivo studies.

The scientific importance of ZNF624 knockout cell lines extends to various research areas, including cellular biology, genetics, and pharmacology. These cell lines serve as invaluable models for understanding gene function and assessing the effects of potential drug candidates. Moreover, their ability to mimic pathological conditions can aid in the discovery of biomarkers and new treatment modalities.

Distinct from traditional gene editing methods, the ZNF624 Gene Knockout Cell Lines offer substantial advantages, including reduced off-target effects and increased efficiency in producing homogeneous populations of genetically modified cells. Additionally, their ready availability and the comprehensive validation process ensure reliability in experimental use, while providing a significant cost-benefit value by saving researchers time and resources in generating their own knockout models.

In conclusion, ZNF624 Gene Knockout Cell Lines are an essential asset for researchers and clinicians aiming to unravel the complexities of gene function and its implications in health and disease. The offering reflects our company’s commitment to providing innovative biological products backed by rigorous scientific expertise and a dedication to advancing research capabilities. Whether in academic or clinical environments, our tools empower the next generation of discoveries in genetics.

Please note that all services are for research use only. Not intended for any clinical use.

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