Gene: ZNF619
Official Full Name: zinc finger protein 619provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12110 | ZNF619 Knockout cell line (HeLa) | Human | ZNF619 | 1:3~1:6 | Negative | Online Inquiry |
KO12111 | ZNF619 Knockout cell line (HCT 116) | Human | ZNF619 | 1:2~1:4 | Negative | Online Inquiry |
KO12112 | ZNF619 Knockout cell line (HEK293) | Human | ZNF619 | 1:3~1:6 | Negative | Online Inquiry |
KO12113 | ZNF619 Knockout cell line (A549) | Human | ZNF619 | 1:3~1:4 | Negative | Online Inquiry |
ZNF619 Gene Knockout Cell Lines are specialized cellular models engineered to lack the ZNF619 gene, which encodes a zinc finger protein that plays a pivotal role in various cellular processes, including transcriptional regulation and cellular response to stress. These knockout cell lines enable researchers to investigate the specific contributions of ZNF619 to gene expression, cell signaling, and developmental pathways by providing a controlled genetic background for comparative studies.
The key function of ZNF619 gene knockout cell lines lies in their ability to elucidate gene function and interaction networks. By eliminating the expression of the ZNF619 protein, researchers can examine downstream effects on cellular behavior, including proliferation, apoptosis, and differentiation. This mechanism of action empowers scientists to explore gene-specific pathways and their implications in disease models, particularly in conditions where zinc finger proteins are implicated, such as cancers and neurodegenerative disorders.
The scientific importance of these knockout cell lines extends into both research and clinical applications. In the research setting, they serve as invaluable tools for study in functional genomics and vector development. Clinically, they hold promise for understanding the underlying mechanisms of disease, aiding in the identification of novel therapeutic targets, and facilitating drug discovery processes.
What sets ZNF619 gene knockout cell lines apart from traditional cell line models is their precise gene editing capabilities, achieving a high fidelity in the knockout processes compared to non-specific RNA interference techniques. Additionally, they offer a stable and reproducible model that minimizes off-target effects, thereby providing more reliable data and enhancing the integrity of experimental outcomes.
For researchers and clinicians seeking to unravel the complexities of gene regulation and its implications for human health, ZNF619 gene knockout cell lines represent an essential resource. They empower scientists to drive advancements in genetic research and therapeutic innovation. Our company, with its commitment to providing cutting-edge biological products, leverages advanced genetic engineering techniques to ensure that our offerings meet the highest standards of quality and efficacy in the life sciences domain.
Please note that all services are for research use only. Not intended for any clinical use.
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