Gene: ZNF606
Official Full Name: zinc finger protein 606provided by HGNC
Gene Summary: This gene encodes a zinc finger protein containing a Kruppel-associated box (KRAB) domain at its N-terminus, followed by contiguous C2H2 zinc finger motifs. The encoded protein is a nuclear protein that can act as a transcriptional repressor of growth factor-mediated signaling pathways in a reporter gene assay. This protein has been shown to interact with the SRY-box 9 gene product, and suppresses its transcriptional activity by inhibiting its DNA binding activity. Reduced expression of this gene promotes chondrocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26239 | ZNF606 Knockout cell line (HEK293) | Human | ZNF606 | 1:3~1:6 | Negative | Online Inquiry |
KO26240 | ZNF606 Knockout cell line (A549) | Human | ZNF606 | 1:3~1:4 | Negative | Online Inquiry |
ZNF606 Gene Knockout Cell Lines are precisely engineered cellular models where the ZNF606 gene, implicated in various biological processes and diseases, has been disrupted or entirely removed. These knockout cell lines allow researchers to investigate the specific roles of the ZNF606 gene in gene expression regulation, cellular differentiation, and disease mechanisms, providing insights that are critical for understanding its functional impacts in both normal physiology and pathophysiology.
The primary function of the ZNF606 knockout cell lines is to serve as a versatile tool for loss-of-function studies. By observing changes in cellular behavior, protein interactions, and gene expression patterns in the absence of ZNF606, researchers can elucidate its contribution to pathways relevant to oncology, neurobiology, and metabolic disorders. The technology usually incorporates CRISPR-Cas9 gene editing, which promotes precise alterations to the genome, ensuring specificity in targeting the ZNF606 gene while minimizing off-target effects.
The scientific importance of these cell lines cannot be overstated. They have broad applications in fundamental research, drug discovery, and therapeutic development. With the ZNF606 gene associated with various diseases, knockout models provide invaluable systems to test hypotheses and evaluate potential therapeutic strategies aimed at correcting the dysregulation associated with ZNF606 function.
Unique advantages of ZNF606 Gene Knockout Cell Lines include their high degree of fidelity and reproducibility, enabling rigorous scientific experiments. Compared to traditional knockout methods, such as those relying on homologous recombination, CRISPR-Cas9 provides a more efficient pathway for gene editing with enhanced precision. These cell lines are readily adaptable and can be utilized in various cell types, making them a powerful addition to many laboratories.
For researchers and clinicians, the ability to study the ZNF606 gene in a controlled environment opens new pathways for discovering novel treatment options and understanding complex biological processes. By investing in ZNF606 Gene Knockout Cell Lines, you gain access to a state-of-the-art resource that is essential for advancing your research capabilities.
Our company prides itself on delivering high-quality, innovative biological products, developed through rigorous scientific research and expertise. We are committed to empowering the scientific community with cutting-edge tools that promise to enhance discovery and foster advancements in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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