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ZNF586 Knockout Cell Lines

Gene: ZNF586

Official Full Name: zinc finger protein 586provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12138 ZNF586 Knockout cell line (HeLa) Human ZNF586 1:3~1:6 Negative Online Inquiry
KO12139 ZNF586 Knockout cell line (HCT 116) Human ZNF586 1:2~1:4 Negative Online Inquiry
KO12140 ZNF586 Knockout cell line (HEK293) Human ZNF586 1:3~1:6 Negative Online Inquiry
KO12141 ZNF586 Knockout cell line (A549) Human ZNF586 1:3~1:4 Negative Online Inquiry

Background

ZNF586 Gene Knockout Cell Lines are genetically modified cell lines in which the ZNF586 gene has been rendered non-functional through targeted gene editing techniques. This specific gene is implicated in various biological processes, including cell proliferation and differentiation, making its study crucial for understanding its role in disease pathways. The knockout of ZNF586 allows researchers to elucidate the gene's functions by observing the phenotypic changes that occur in its absence, providing important insights into its contributions to cellular homeostasis and potential connections to pathologies such as cancer.

The primary mechanism behind these cell lines involves the use of CRISPR-Cas9 technology, which enables precise and efficient editing of the genome. By introducing double-strand breaks at the ZNF586 locus, the repair mechanisms of the cell facilitate the knockout, leading to the subsequent expression of truncated or non-functional proteins. This precise targeting allows researchers to confidently assess the downstream effects of ZNF586 loss, which is invaluable for both fundamental biology and translational research.

The scientific significance of ZNF586 Gene Knockout Cell Lines extends to various research areas, including gene function studies, drug development, and the investigation of molecular pathways in disease contexts. In clinical settings, these cell lines can serve as models for testing new therapeutic strategies or studying patient-specific mutations associated with conditions linked to ZNF586.

What sets our ZNF586 Gene Knockout Cell Lines apart from alternative products is their exceptional purity and validated genetic modification, ensuring reproducible and reliable results. Our cells are optimized for high growth rates and are compatible with a wide range of applications, from biochemical assays to high-throughput screening.

These cell lines represent a crucial tool for researchers aiming to reveal unknown functions of the ZNF586 gene and its implications in health and disease. By investing in this product, researchers and clinicians gain a powerful resource to support their investigations and therapeutic development efforts.

With years of experience in gene editing technologies and a commitment to advancing biological research, our company provides superior gene knockout cell lines, facilitating groundbreaking discoveries in the realm of genetics and molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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