Gene: ZNF549
Official Full Name: zinc finger protein 549provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21070 | ZNF549 Knockout cell line (HEK293) | Human | ZNF549 | 1:3~1:6 | Negative | Online Inquiry |
KO21071 | ZNF549 Knockout cell line (A549) | Human | ZNF549 | 1:3~1:4 | Negative | Online Inquiry |
ZNF549 Gene Knockout Cell Lines are a specialized biological tool designed for researchers seeking to investigate the functional roles of the ZNF549 gene in various cellular processes and diseases. These cell lines are generated using advanced gene-editing technologies, such as CRISPR-Cas9, which effectively disable the expression of the ZNF549 gene, allowing for a more profound understanding of its contributions to transcriptional regulation and cellular signaling pathways.
The primary function of ZNF549 Gene Knockout Cell Lines lies in their ability to create a controlled environment for studying gene function and gene interaction in vitro. By knocking out the ZNF549 gene, researchers can observe the resulting phenotypic changes, alterations in gene expression patterns, and the effects on cellular behavior under various conditions. This mechanism provides critical insights into the role of ZNF549 in developmental biology and pathology, particularly in cancer research, where dysregulation of zinc finger proteins has been implicated.
The scientific importance of these knockout cell lines is underscored by their applicability in both basic research and clinical settings. They serve as foundational models for drug discovery and therapeutic interventions, enabling the testing of new compounds targeting ZNF549-related pathways. Additionally, they provide a platform for understanding the biological implications of ZNF549 in diseases, thus fostering the development of potential biomarkers and treatment strategies.
In comparison to other genetic modifications, ZNF549 Gene Knockout Cell Lines offer distinct advantages by providing precise and permanent alterations to the genome, ensuring reproducibility and consistency across experiments. This specificity reduces off-target effects commonly faced with older technologies, enhancing the reliability of experimental outcomes.
Researchers, clinicians, and biotechnology companies will find great value in ZNF549 Gene Knockout Cell Lines due to their potential to accelerate discoveries in gene function, pathophysiology, and therapeutic development. By utilizing these cell lines, professionals can contribute to advancing scientific knowledge and improving patient outcomes.
Our company specializes in the development and supply of high-quality gene knockout models, leveraging cutting-edge technologies and extensive expertise. With a commitment to innovation and excellence, we ensure that our products meet the rigorous standards needed for impactful research and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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