Gene: ZNF547
Official Full Name: zinc finger protein 547provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12173 | ZNF547 Knockout cell line (HeLa) | Human | ZNF547 | 1:3~1:6 | Negative | Online Inquiry |
KO12174 | ZNF547 Knockout cell line (HCT 116) | Human | ZNF547 | 1:2~1:4 | Negative | Online Inquiry |
KO12175 | ZNF547 Knockout cell line (HEK293) | Human | ZNF547 | 1:3~1:6 | Negative | Online Inquiry |
KO12176 | ZNF547 Knockout cell line (A549) | Human | ZNF547 | 1:3~1:4 | Negative | Online Inquiry |
ZNF547 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to inactivate the ZNF547 gene through targeted homologous recombination. These cell lines serve as vital tools in molecular biology, allowing researchers to elucidate the gene's role in various biological processes, including cell differentiation, proliferation, and apoptosis. The knockout mechanism is facilitated by CRISPR-Cas9 technology, which introduces specific mutations into the ZNF547 gene, resulting in a loss of function. This approach not only provides a more accurate model for studying gene function but also enables researchers to observe phenotypic changes that occur as a result of the genetic alteration.
The scientific importance of ZNF547 Gene Knockout Cell Lines extends to their applications in both basic research and clinical settings. In fundamental research, these cell lines enable scientists to explore the regulatory pathways and interactions associated with ZNF547, contributing to our understanding of diseases such as cancer, where zinc finger proteins can have a significant impact on tumorigenesis and metastasis. Additionally, they hold potential for developing targeted therapeutic strategies, as understanding the role of specific genes can lead to more effective treatments.
Compared to traditional gene silencing methods, such as RNA interference, ZNF547 Gene Knockout Cell Lines offer distinct advantages, including permanent gene inactivation and stable integration into the genome. This stability allows for long-term studies and reduces variability caused by transient knockdown. As a result, researchers can obtain more reproducible and consistent data.
For researchers and clinicians alike, the value of ZNF547 Gene Knockout Cell Lines lies in their ability to drive discovery and innovation in gene function research. They provide a robust platform that can lead to breakthroughs in understanding genetic contributions to diseases and the development of novel therapies.
At [Your Company Name], we pride ourselves on our commitment to delivering high-quality biological products that empower the scientific community. Our expertise in gene editing and cell line development ensures that we provide reliable tools that enhance research and contribute to advancements in biomedical science.
Please note that all services are for research use only. Not intended for any clinical use.
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