Gene: ZNF516
Official Full Name: zinc finger protein 516provided by HGNC
Gene Summary: Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a zinc-finger protein, and belongs to the krueppel C2H2-type zinc-finger protein family. It may be involved in transcriptional regulation. [provided by RefSeq, Sep 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32958 | ZNF516 Knockout cell line (HCT 116) | Human | ZNF516 | 1:2~1:4 | Negative | Online Inquiry |
KO32959 | ZNF516 Knockout cell line (HEK293) | Human | ZNF516 | 1:3~1:6 | Negative | Online Inquiry |
KO32960 | ZNF516 Knockout cell line (A549) | Human | ZNF516 | 1:3~1:4 | Negative | Online Inquiry |
ZNF516 Gene Knockout Cell Lines are specifically engineered cellular models that have had the Zinc Finger Protein 516 (ZNF516) gene disrupted or “knocked out.” This modification allows researchers to study the role of ZNF516 in various biological processes, including gene regulation, cellular differentiation, and disease models. The ZNF516 gene is implicated in mechanisms relating to transcriptional regulation and epigenetic control, making its investigation crucial for understanding various pathological states, especially in cancer and metabolic disorders.
These cell lines operate by utilizing CRISPR/Cas9 genome-editing technology, granting precise alterations that facilitate the observation of phenotypic variations in response to environmental stimuli or drug treatments. By eliminating ZNF516 expression, researchers can elucidate its function and interactions with other genes and proteins, paving the way for innovative therapeutic strategies. The ability to toggle specific genetic inputs further enhances the functionality of these models in pharmacological testing and fundamental research.
The scientific importance of ZNF516 Gene Knockout Cell Lines extends into both research and clinical applications. In research contexts, these models serve as critical tools for the understanding of gene function and disease mechanisms. Clinically, they offer potential insights into targeted therapies and personalized medicine approaches, given ZNF516's emerging role in tumorigenesis and cellular metabolism.
What sets these knockout cell lines apart from traditional wild-type models is their capacity for precise gene disruption, which leads to reproducible and relevant data. Unlike other gene-editing products, the knockout technology minimizes off-target effects and enhances the specificity of gene analysis. As a result, researchers and clinicians can gain a clearer understanding of ZNF516's role without the confounding factors often present in less optimized models.
In essence, ZNF516 Gene Knockout Cell Lines are invaluable for advancing our knowledge of gene function and disease, making them crucial for both preclinical and translational studies. Our company prides itself on providing high-quality biological tools, supported by rigorous research and development, ensuring that researchers and clinicians can rely on our offerings to elucidate complex biological questions effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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