Gene: ZNF500
Official Full Name: zinc finger protein 500provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28436 | ZNF500 Knockout cell line (HeLa) | Human | ZNF500 | 1:3~1:6 | Negative | Online Inquiry |
KO28437 | ZNF500 Knockout cell line (HCT 116) | Human | ZNF500 | 1:2~1:4 | Negative | Online Inquiry |
KO28438 | ZNF500 Knockout cell line (HEK293) | Human | ZNF500 | 1:3~1:6 | Negative | Online Inquiry |
KO28439 | ZNF500 Knockout cell line (A549) | Human | ZNF500 | 1:3~1:4 | Negative | Online Inquiry |
ZNF500 Gene Knockout Cell Lines are sophisticated, genetically modified cellular systems designed to facilitate high-precision studies of the ZNF500 gene's functions. The ZNF500 gene, a member of the zinc finger protein family, is implicated in various cellular processes, including gene regulation, cell differentiation, and response to stress. These knockout cell lines utilize targeted genome editing technologies, primarily CRISPR-Cas9, to disrupt the ZNF500 gene, effectively creating models that allow researchers to elucidate its role in cellular mechanisms and pathology.
The primary function of ZNF500 Gene Knockout Cell Lines is to serve as a tool for functional genomics and phenotypic analysis. By removing the gene associated with critical pathways, researchers can observe resultant changes in cellular behavior, signaling cascades, and gene expression profiles. This enables a deeper understanding of gene function and its implications in diseases such as cancer, neurological disorders, and metabolic syndromes.
Scientifically, these knockout models represent invaluable resources in both research and clinical contexts. They not only facilitate the investigation of ZNF500 directly but also broaden the scope of study to related gene networks, thus offering insights into multifactorial diseases. Additionally, ZNF500 knockout lines can be pivotal in drug discovery and personalized medicine by helping to identify potential therapeutic targets and assess compound efficacy.
What sets ZNF500 Gene Knockout Cell Lines apart from traditional alternatives is their enhanced specificity and reproducibility, ensuring that researchers have reliable tools for their investigations. Unlike transient knockdown methods that can produce variable results, these stable lines allow for consistent and long-term studies, significantly improving experimental reliability.
For researchers and clinicians focused on the intricacies of gene function and therapeutic interventions, ZNF500 Gene Knockout Cell Lines represent a vital addition to their toolkit. With our company's extensive expertise in genetic engineering and cell line development, we provide high-quality, validated products to advance scientific discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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