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ZNF461 Knockout Cell Lines

Gene: ZNF461

Official Full Name: zinc finger protein 461provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23227 ZNF461 Knockout cell line (HEK293) Human ZNF461 1:3~1:6 Negative Online Inquiry
KO23228 ZNF461 Knockout cell line (A549) Human ZNF461 1:3~1:4 Negative Online Inquiry

Background

ZNF461 Gene Knockout Cell Lines are specialized cellular models that have been engineered to lack the zinc finger protein 461 (ZNF461) gene. This product allows researchers to investigate the biological functions and regulatory mechanisms associated with ZNF461, a transcription factor implicated in various cellular processes, including development, differentiation, and response to stress. By providing a precise genetic alteration, these knockout cell lines serve as a crucial tool for elucidating the gene's role in both normal physiology and disease mechanisms.

The mechanism behind ZNF461 knockout involves the targeted disruption of the ZNF461 gene using CRISPR/Cas9 technology, which ensures high specificity and efficiency in gene editing. Researchers can utilize these cell lines to assess the impact of ZNF461 absence on cellular behavior, gene expression profiles, and signaling pathways, thereby uncovering its roles in disease contexts such as cancer or metabolic disorders.

The scientific importance of ZNF461 Gene Knockout Cell Lines lies in their applicability in a wide range of research settings, from fundamental biology to drug discovery. By facilitating the study of gene function and interaction with other molecular players, these cell lines enable advancements in understanding genetic contributions to health and disease, ultimately leading to more effective therapeutic strategies.

Compared to conventional wild-type cell lines and other gene knockout technologies, ZNF461 Gene Knockout Cell Lines offer a distinct advantage in their tailored genetic modification and reproducibility. This specificity enhances the reliability of experimental outcomes, providing researchers with confidence in their findings and interpretations.

Valuable to both researchers and clinicians, these cell lines represent an essential resource for those investigating gene-function relationships and exploring innovative approaches for targeted therapies. With a strong commitment to advancing genetic research, our company leverages state-of-the-art technologies to deliver high-quality biological products, ensuring that scientists are equipped with the best tools to drive groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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