Gene: ZNF441
Official Full Name: zinc finger protein 441provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27456 | ZNF441 Knockout cell line (HeLa) | Human | ZNF441 | 1:3~1:6 | Negative | Online Inquiry |
KO27457 | ZNF441 Knockout cell line (HCT 116) | Human | ZNF441 | 1:2~1:4 | Negative | Online Inquiry |
KO27458 | ZNF441 Knockout cell line (HEK293) | Human | ZNF441 | 1:3~1:6 | Negative | Online Inquiry |
ZNF441 Gene Knockout Cell Lines are specialized cellular systems engineered to lack the expression of the ZNF441 gene, which encodes a transcription factor implicated in numerous cellular processes, including cell proliferation, apoptosis, and differentiation. By utilizing CRISPR/Cas9 technology, ZNF441 is precisely targeted for deletion, allowing researchers to study the resulting phenotypic changes in a controlled environment. This gene knockout model serves as a vital tool for understanding the biological pathways regulated by ZNF441 and elucidating its role in disease mechanisms, particularly in cancer and genetic disorders.
The primary function of ZNF441 Gene Knockout Cell Lines is to facilitate the investigation of gene function through loss-of-function studies. Upon knockout, researchers can observe alterations in cell behavior, signaling pathways, and gene expression profiles, providing insights into the biological significance of ZNF441. These cell lines can be further utilized in drug discovery efforts, allowing for the assessment of therapeutic interventions targeting pathways influenced by ZNF441.
The scientific importance of ZNF441 Gene Knockout Cell Lines extends to both basic research and clinical applications. They are indispensable in functional genomics studies and biomarker discovery, situating them as essential tools within laboratories focusing on cancer biology, developmental biology, and regenerative medicine.
Compared to traditional gene knockout methods, ZNF441 Gene Knockout Cell Lines offer higher precision, efficiency, and reproducibility, significantly reducing the time and resources required for gene editing. Their viability and ease of use in various experimental settings enhance their appeal over competing products, which may suffer from variations or limitations in modification efficiency.
For researchers and clinicians aiming to unravel the complexities of gene regulation and its implications for human health, ZNF441 Gene Knockout Cell Lines provide an innovative and reliable solution. They not only enable comprehensive studies of gene function but also pave the way for therapeutic advancements by identifying novel targets based on ZNF441-related pathways.
As a company dedicated to advancing scientific research, our expertise lies in developing cutting-edge biological products that empower scientists and clinicians alike. Our commitment to quality ensures that ZNF441 Gene Knockout Cell Lines are robust, reliable, and ready to support groundbreaking research across various disciplines.
Please note that all services are for research use only. Not intended for any clinical use.
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