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ZNF432 Knockout Cell Lines

Gene: ZNF432

Official Full Name: zinc finger protein 432provided by HGNC

Gene Summary: Enables damaged DNA binding activity and protein-macromolecule adaptor activity. Involved in DNA damage response. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00904 ZNF432 Knockout cell line(U-2 OS) Human ZNF432 1:3~1:5 Negative Online Inquiry
KO00905 ZNF432 Knockout cell line (HeLa) Human ZNF432 1:3~1:6 Negative Online Inquiry
KO12232 ZNF432 Knockout cell line (HEK293) Human ZNF432 1:3~1:6 Negative Online Inquiry
KO12233 ZNF432 Knockout cell line (A549) Human ZNF432 1:3~1:4 Negative Online Inquiry

Background

ZNF432 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the ZNF432 gene, a critical component involved in various cellular processes, including gene regulation, cell proliferation, and differentiation. By utilizing CRISPR-Cas9 technology, these cell lines have been meticulously constructed to eliminate the ZNF432 gene's expression, allowing researchers to dissect its role in different biological pathways and disease states.

The primary function of ZNF432 Gene Knockout Cell Lines is to provide a robust platform for functional genomic studies. When ZNF432 is disrupted, the resulting phenotypic changes can elucidate its contribution to processes such as tumorigenesis or metabolic regulation. Researchers can analyze these cell lines under various experimental conditions to determine the impact of ZNF432 knockout on signaling pathways, gene expression profiles, and cellular responses to stimuli. This knockdown model is invaluable for understanding the gene’s role in health and disease, paving the way for potential therapeutic strategies targeting ZNF432-related disorders.

From a scientific perspective, the development of ZNF432 Gene Knockout Cell Lines is crucial for advancing our understanding in molecular biology and genetics, particularly in relation to its implications in cancers and metabolic diseases. The specificity and precision of CRISPR technology offer significant advantages over traditional gene-editing methods, resulting in fewer off-target effects, higher knockout efficiency, and clearer interpretation of observed results.

Compared to alternative models, such as RNA interference or traditional knockout strategies, ZNF432 Gene Knockout Cell Lines stand out due to their stable and permanent gene deletion, enabling more reliable long-term studies. This unique differentiation maximizes experimental reproducibility and consistency—critical factors for researchers dedicated to advancing their fields of study.

For researchers and clinicians, utilizing ZNF432 Gene Knockout Cell Lines can lead to groundbreaking discoveries in understanding molecular mechanisms of disease, potentially influencing therapeutic interventions. With our proven expertise in creating high-quality biological products, our company is dedicated to supporting advancing research and improving clinical outcomes through innovative cellular models like these knockout cell lines.

Please note that all services are for research use only. Not intended for any clinical use.

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