Gene: ZNF398
Official Full Name: zinc finger protein 398provided by HGNC
Gene Summary: This gene encodes a member of the Kruppel family of C2H2-type zinc-finger transcription factor proteins. The encoded protein acts as a transcriptional activator. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described, but their full length sequence has not been determined. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12263 | ZNF398 Knockout cell line (HeLa) | Human | ZNF398 | 1:3~1:6 | Negative | Online Inquiry |
KO12264 | ZNF398 Knockout cell line (HCT 116) | Human | ZNF398 | 1:2~1:4 | Negative | Online Inquiry |
KO12265 | ZNF398 Knockout cell line (HEK293) | Human | ZNF398 | 1:3~1:6 | Negative | Online Inquiry |
KO12266 | ZNF398 Knockout cell line (A549) | Human | ZNF398 | 1:3~1:4 | Negative | Online Inquiry |
ZNF398 Gene Knockout Cell Lines are a powerful biological tool designed for researchers investigating the functional roles of the ZNF398 gene, a key player in gene regulation, cellular stress response, and oncogenesis. These cell lines are genetically engineered to display a complete knockout of the ZNF398 gene, allowing for precise studies regarding its contributions to various biological processes and diseases.
The primary function of ZNF398 Gene Knockout Cell Lines is to facilitate the exploration of ZNF398's role in cellular mechanisms. By removing the gene's influence, researchers can analyze subsequent changes in gene expression profiles, signaling pathways, and cellular behaviors, such as proliferation, differentiation, and apoptosis. The knockout serves as a baseline for understanding the gene’s specific contributions, enabling the identification of potential therapeutic targets in cancer and other disorders.
The scientific importance of ZNF398 Gene Knockout Cell Lines extends to multiple fields, including cancer biology, stem cell research, and regenerative medicine. With growing evidence linking ZNF398 to tumor progression and resistance to therapies, these cell lines provide invaluable insights into the enigmatic relationship between gene regulation and disease mechanisms. Their application in drug discovery and preclinical studies further supports their utility in translational research.
Compared to alternative models, such as wild-type cells or transient knockdown systems, ZNF398 Gene Knockout Cell Lines offer increased stability and reproducibility in experimental results. The engineered cells present a consistent genetic background, which allows for clearer interpretations of experimental outcomes without the variability often encountered in transient gene editing methodologies.
For researchers, clinicians, and biotechnologists focused on uncovering gene functions and developing targeted therapies, ZNF398 Gene Knockout Cell Lines represent a robust and reliable resource. They amplify the potential for innovative discoveries and therapeutic advancements that can address pressing health-related challenges.
Our company’s expertise in providing high-quality genetic models, complemented by robust customer support, ensures that you will have the tools necessary to propel your research forward and unlock new avenues in your scientific endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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