Gene: ZNF37A
Official Full Name: zinc finger protein 37Aprovided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34683 | ZNF37A Knockout cell line (HeLa) | Human | ZNF37A | 1:3~1:6 | Negative | Online Inquiry |
KO34684 | ZNF37A Knockout cell line (HCT 116) | Human | ZNF37A | 1:2~1:4 | Negative | Online Inquiry |
KO34685 | ZNF37A Knockout cell line (HEK293) | Human | ZNF37A | 1:3~1:6 | Negative | Online Inquiry |
KO34686 | ZNF37A Knockout cell line (A549) | Human | ZNF37A | 1:3~1:4 | Negative | Online Inquiry |
ZNF37A Gene Knockout Cell Lines consist of genetically modified cell lines where the ZNF37A gene has been precisely disrupted using CRISPR-Cas9 genome-editing technology. This gene encodes a zinc finger protein implicated in various cellular processes, including transcription regulation and cellular differentiation. The creation of these cell lines allows researchers to study the specific role of ZNF37A in various biological pathways and potential disease mechanisms, fundamentally advancing our understanding of gene function in both health and disease.
The key mechanism of action for ZNF37A Gene Knockout Cell Lines lies in their ability to facilitate the examination of loss-of-function phenotypes associated with the absence of ZNF37A. By providing an environment in which researchers can assess how the perturbation of this gene influences cellular behavior, such as proliferation, apoptosis, and differentiation, these cell lines serve as invaluable tools for elucidating the biological implications of ZNF37A activity. This functional insight is pivotal in fields like oncology, developmental biology, and gene therapy research.
The scientific importance of ZNF37A Gene Knockout Cell Lines is underscored by their diverse applications. They are instrumental in preclinical studies aimed at identifying new therapeutic targets, exploring the molecular underpinnings of diseases like cancer, and testing drug efficacy in a controlled environment. These cell lines empower researchers to bridge the gap between molecular biology insights and therapeutic developments, making them essential for innovative research.
Compared to alternative models such as wild-type cell lines or other knockout systems, ZNF37A Gene Knockout Cell Lines offer superior specificity and reliability in studying the exact contributions of the ZNF37A gene. The precision of CRISPR-Cas9 technology ensures that off-target effects are minimized, allowing for clearer interpretations of experimental outcomes.
In summary, ZNF37A Gene Knockout Cell Lines represent a significant asset for researchers and clinicians focused on understanding gene function and its implications in health and disease. Their capacity to facilitate targeted studies establishes them as an indispensable platform in biomedical research. Our company, with its extensive expertise in genetic engineering and cell line development, is dedicated to providing high-quality biological products that support scientific advancement and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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