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ZNF343 Knockout Cell Lines

Gene: ZNF343

Official Full Name: zinc finger protein 343provided by HGNC

Gene Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22128 ZNF343 Knockout cell line (HeLa) Human ZNF343 1:3~1:6 Negative Online Inquiry
KO22129 ZNF343 Knockout cell line (HCT 116) Human ZNF343 1:2~1:4 Negative Online Inquiry
KO22130 ZNF343 Knockout cell line (HEK293) Human ZNF343 1:3~1:6 Negative Online Inquiry
KO22131 ZNF343 Knockout cell line (A549) Human ZNF343 1:3~1:4 Negative Online Inquiry

Background

ZNF343 Gene Knockout Cell Lines represent an innovative tool specifically designed for the study of gene function and regulation in cellular contexts. These cell lines are genetically engineered to disable the ZNF343 gene, allowing researchers to explore its role in various biological processes, including transcriptional regulation and cellular responses to stress. By utilizing CRISPR-Cas9 technology, ZNF343 gene knockout cell lines provide a powerful platform for studying how the absence of this gene affects cellular behavior, signaling pathways, and gene expression profiles.

The key mechanism underlying these cell lines involves the targeted editing of the ZNF343 gene, leading to a frameshift mutation or a complete deletion. This precise gene knockout ensures that any observed phenotypic changes can be directly attributed to the lack of ZNF343 expression. Through various assays, researchers can assess alterations in cell proliferation, apoptosis, and response to environmental factors, potentially revealing novel therapeutic targets and biomolecular pathways.

From a scientific perspective, the ability to manipulate the ZNF343 gene offers significant applications in both fundamental research and clinical translational studies. Investigations using these knockout cell lines can contribute to a deeper understanding of cancer biology, developmental disorders, and other pathophysiological conditions linked to dysregulated gene expression.

What sets ZNF343 Gene Knockout Cell Lines apart from conventional research tools is their specificity and robustness. Unlike prior methods that may produce ambiguous results due to off-target effects, the precision of CRISPR technology ensures that researchers can achieve reliable and reproducible outcomes. Furthermore, these cell lines enable high-throughput screening and provide an excellent framework for collaborative research aimed at drug discovery and genetic studies.

For researchers and clinicians seeking reliable models that elucidate the biological implications of gene function, ZNF343 Gene Knockout Cell Lines are an invaluable resource. Our company is committed to advancing biological research by offering high-quality gene knockout models, backed by extensive expertise and a dedication to supporting advancements in both academic and clinical settings.

Please note that all services are for research use only. Not intended for any clinical use.

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