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ZNF33B Knockout Cell Lines

Gene: ZNF33B

Official Full Name: zinc finger protein 33Bprovided by HGNC

Gene Summary: This gene encodes a member of the zinc finger family of proteins. This gene shows decreased expression in cumulus cells derived from patients undergoing controlled ovarian stimulation. This gene is present in a gene cluster with several related zinc finger genes in the pericentromeric region of chromosome 10. Pseudogenes have been identified on chromosomes 7 and 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34687 ZNF33B Knockout cell line (HeLa) Human ZNF33B 1:3~1:6 Negative Online Inquiry
KO34688 ZNF33B Knockout cell line (HCT 116) Human ZNF33B 1:2~1:4 Negative Online Inquiry
KO34689 ZNF33B Knockout cell line (HEK293) Human ZNF33B 1:3~1:6 Negative Online Inquiry
KO34690 ZNF33B Knockout cell line (A549) Human ZNF33B 1:3~1:4 Negative Online Inquiry

Background

ZNF33B Gene Knockout Cell Lines are genetically engineered human cell lines in which the ZNF33B gene has been specifically inactivated. These cell lines serve as invaluable tools for researchers investigating the functional role of the ZNF33B gene, a zinc finger protein implicated in various cellular processes, including gene regulation and chromatin remodeling. By effectively eliminating the expression of ZNF33B, these knockout models allow scientists to delineate the gene's contribution to pathophysiological conditions, ranging from developmental disorders to cancers.

The key functions of ZNF33B involve its regulatory capacity on gene transcription, impacting pathways critical for cellular proliferation and differentiation. Utilizing CRISPR-Cas9 technology, our ZNF33B Gene Knockout Cell Lines exhibit precise gene editing, ensuring the integrity and specificity of the knockout process. This can lead to clearer insights into gene function, especially in contexts where ZNF33B is suspected to play a crucial role. Studies utilizing these cell lines can reveal how perturbed expression of ZNF33B affects cellular behavior, which is pivotal for understanding diseases marked by dysregulated transcription factors.

From a scientific standpoint, these knockout cell lines have broad applications, notably in drug development and personalized medicine, where understanding the molecular underpinnings of diseases is paramount. Their use can accelerate discoveries in gene therapy, regenerative medicine, and cancer research, making them essential for a variety of experimental approaches.

Compared to alternative gene-editing models, our ZNF33B Gene Knockout Cell Lines boast high efficiency and reproducibility, underpinned by our commitment to quality and technological advancements in the field. Researchers will appreciate the reliability of these models in delivering consistent data across multiple experiments, thereby enhancing overall research productivity.

Ultimately, the development of ZNF33B Gene Knockout Cell Lines represents a significant advancement in molecular biology tools, offering researchers and clinicians an unparalleled opportunity to investigate gene function in health and disease. With years of experience in molecular genetics and a portfolio of high-quality biological products, our company is dedicated to supporting scientific advancement through innovative solutions that empower the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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