Gene: ZNF281
Official Full Name: zinc finger protein 281provided by HGNC
Gene Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of gene expression; negative regulation of transcription by RNA polymerase II; and positive regulation of DNA-templated transcription. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12329 | ZNF281 Knockout cell line (HeLa) | Human | ZNF281 | 1:3~1:6 | Negative | Online Inquiry |
KO12330 | ZNF281 Knockout cell line (HCT 116) | Human | ZNF281 | 1:2~1:4 | Negative | Online Inquiry |
KO12331 | ZNF281 Knockout cell line (HEK293) | Human | ZNF281 | 1:3~1:6 | Negative | Online Inquiry |
KO12332 | ZNF281 Knockout cell line (A549) | Human | ZNF281 | 1:3~1:4 | Negative | Online Inquiry |
ZNF281 Gene Knockout Cell Lines are specifically engineered human cell lines that possess a targeted deletion of the ZNF281 gene, a critical regulator of various cellular processes including stem cell maintenance and differentiation. This advanced biological tool is designed to aid researchers in understanding the role of ZNF281 in cellular behavior, gene expression, and developmental biology.
These knockout cell lines function through a mechanism of homologous recombination, which eliminates the ZNF281 gene, allowing for the observation of phenotypic changes that occur in the absence of this gene. This technology enables researchers to probe deeper into the pathways regulated by ZNF281 and its implications in diseases, particularly in cancer and regenerative medicine. By comparing the knockout cell lines to wild-type counterparts, scientists can assess changes in cell morphology, proliferation rates, and differentiation capabilities, providing crucial insights into the gene’s function.
The scientific importance of ZNF281 Gene Knockout Cell Lines extends to both fundamental research and clinical applications, particularly in oncology where understanding gene functions can lead to novel therapeutic targets. Moreover, these cell lines facilitate high-throughput screening for drug discovery and pave the way for potential advancements in gene therapy.
A distinct advantage of our ZNF281 Gene Knockout Cell Lines is their validated and stable knockout status, providing consistency and reliability in experimental settings. Unlike alternative products that may offer less characterized knockout models, these cell lines come with comprehensive data supporting their performance and functional validity, ensuring researchers can trust their experimental outcomes.
For researchers and clinicians aiming to decode the roles of transcription factors and their associated pathways, ZNF281 Gene Knockout Cell Lines represent an invaluable asset. These cell lines not only enhance experimental precision but also contribute significantly to advancing knowledge in pivotal areas of cell biology and therapeutic development.
At [Your Company Name], we specialize in providing high-quality biological products that empower scientific breakthroughs. Our expertise in gene editing technologies ensures that you have access to trusted resources like the ZNF281 Gene Knockout Cell Lines, facilitating impactful research across multiple disciplines.
Please note that all services are for research use only. Not intended for any clinical use.
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