Gene: ZNF275
Official Full Name: zinc finger protein 275provided by HGNC
Gene Summary: This gene encodes a zinc finger protein that appears to be conserved in eutheria. Its function has not yet been established. [provided by RefSeq, Jul 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31461 | ZNF275 Knockout cell line (HeLa) | Human | ZNF275 | 1:3~1:6 | Negative | Online Inquiry |
KO31462 | ZNF275 Knockout cell line (HCT 116) | Human | ZNF275 | 1:2~1:4 | Negative | Online Inquiry |
KO31463 | ZNF275 Knockout cell line (HEK293) | Human | ZNF275 | 1:3~1:6 | Negative | Online Inquiry |
KO31464 | ZNF275 Knockout cell line (A549) | Human | ZNF275 | 1:3~1:4 | Negative | Online Inquiry |
ZNF275 Gene Knockout Cell Lines are engineered cellular models designed to facilitate the study of the ZNF275 gene's function and its role in various biological processes. By employing CRISPR-Cas9 technology, these cell lines have been specifically modified to lack the ZNF275 gene, enabling researchers to investigate the consequences of gene loss on cell behavior, signaling pathways, and gene regulatory networks. This knockout approach is vital for elucidating the functional relevance of ZNF275 in cellular metabolism, differentiation, and response to stress, providing a platform for broad applications in molecular biology and genetics.
The key mechanism underlying the utility of ZNF275 Gene Knockout Cell Lines lies in their ability to mimic phenotypic effects seen in vivo, which may include altered cellular proliferation, apoptosis, or response to pharmaceutical agents. By comparing knockout cells to their wild-type counterparts, researchers can dissect critical signaling cascades and elucidate the gene's regulatory roles within the cellular context. These investigations have significant implications, particularly in understanding cancer biology, neurodegenerative diseases, and metabolic disorders, where ZNF275 may play a consequential role.
A distinguishing advantage of ZNF275 Gene Knockout Cell Lines is their specificity and reproducibility, characteristics that are often lacking in other experimental models such as xenografts or traditional knockdown approaches. These cell lines provide a robust and controlled environment for experimental dissection, allowing for high-throughput screening applications and validation of therapeutic targets, further enhancing their relevance in preclinical research.
The value of ZNF275 Gene Knockout Cell Lines extends beyond basic research; they serve as essential tools for drug discovery and biomarker development, allowing clinicians and researchers to identify novel therapeutic strategies and personalized medicine approaches. The ability to manipulate these cell lines provides unprecedented insights into gene function and disease mechanisms, ultimately accelerating the pace of biomedical advancements.
Our company brings a wealth of expertise in genetic engineering technologies, ensuring that our ZNF275 Gene Knockout Cell Lines are rigorously validated and characterized for consistent performance in diverse applications. Our commitment to quality and innovation helps researchers and clinicians alike drive forward their scientific inquiries and, ultimately, contribute to better health outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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